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GEFT Antibody, Biotin Conjugated

GEFT Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, GEFT Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenGEFT
SpecificityThis is a highly specific antibody against GEFT
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human GEFT
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Existing as two alternatively spliced variants, GEFT contains a DH (DBL-homology) domain and a PH domain, GEFT is an important regulator of processes involved in axon and dendrite formation, GEFT may play a role in actin cytoskeleton reorganization in different tissues since its activation induces formation of actin stress fibers, GEFT seems to be an exchange factor primarily for Rac 1 in neurons, GEFT works as a guanine nucleotide exchange factor for the Rho family of small GTPases and links specifically to G alpha q/11-coupled receptors in Rho A activation, Involved in skeletal myogenesis, and weakly expressed in small intestine, colon, heart and muscle, liver, placenta and lung, GEFT is a 580 amino acid cytoplasmic protein that is highly expressed in excitable tissues such as brain
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms GEFT p63RhoGEF
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetGEFT Conjugated
Short name Conjugated, GEFT Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, GEFT (Antibody to)
Alternative techniqueantibodies
Identity 30275
Gene ARHGEF25
Long gene name Rho guanine nucleotide exchange factor 25
Synonyms gene name Rho guanine nucleotide exchange factor (GEF) 25
Synonyms name RAC/CDC42 exchange factor
Locus 12q13, 3
Discovery year 2010-09-02
Entrez gene record 115557
Pubmed identfication 12547822
RefSeq identity NM_133483
Classification Rho guanine nucleotide exchange factors
Havana BLAST/BLAT OTTHUMG00000152516

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