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GEMC1 Antibody, FITC Conjugated

GEMC1 Antibody, FITC Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name FITC Conjugated, GEMC1 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenGEMC1
SpecificityThis is a highly specific antibody against GEMC1
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human GEMC1
Gene ID number647309
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background A member of the GEMC1 family, GEMC1 is highly phosphorylated and interacts with chromatin during formation of the pre-replication complex, Key tumor suppressing genes on chromosome 3 encode apoptosis mediator RASSF1, Marfan Syndrome, Notably, Particular regions of the chromosome 3 short arm are deleted in many types of cancer cells, The gene encoding GEMC1 maps to human chromosome 3, cell migration regulator HYAL1 and angiogenesis suppressor SEMA3B, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3, porphyria, there is a chemokine receptor gene cluster and a variety of human cancer related loci on chromosome 3, von Hippel-Lindau syndrome, which is made up of about 214 million bases encoding over 1, 100 genes, GEMC1 is a 334 amino acid nuclear protein that regulates DNA replication by promoting the recruitment of Cdc45 onto replication origins
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms GEMC1
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetGEMC1 Conjugated
Short name FITC Conjugated, GEMC1 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, GEMC1 (Antibody to)
Alternative techniqueantibodies
Identity 40049
Gene GMNC
Long gene name geminin coiled-coil domain containing
Locus 3q28
Discovery year 2011-08-19
GenBank acession BC031680
Entrez gene record 647309
Pubmed identfication 20383140 20855966
RefSeq identity NM_001146686
Havana BLAST/BLAT OTTHUMG00000156195

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