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Gemin 2/SMA Antibody, Cy5 Conjugated

Gemin 2/SMA Antibody, Cy5 Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Cy5 Conjugated, Gemin 2/SMA Polyclonal Antibody
CategoryConjugated Primary Antibodies
Conjugation5, Cy5
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenGemin 2/SMA
SpecificityThis is a highly specific antibody against Gemin 2/SMA
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human Gemin 2
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Gemin2 (formerly known as SIP1 for SMN interacting protein) associates directly with SMN and is a part of the SMN complex containing Gemin3 (a DEAD-box RNA helicase), Gemin2 is expressed in spinal cord, Gemin4, Gemin5 and Gemin6, It can be induced by TGFâ, It is found in both the cytoplasm and the nucleus, SMA is caused by deletion or loss-of-function mutations in the SMN (survival of motor neuron) gene, SMN is expressed in a wide variety of tissues including brain, The SMN complex plays an essential role in splicesomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing of the nucleus, The SMN-Gemin2 complex is associated with spliceosomal snRNAs U1 and U5, The gene encoding Gemin2 maps to human chromosome 14q13, The nuclear form is concentrated in subnuclear bodies called gems (Gemini of the coiled bodies), and moderately in skeletal and cardiac muscle, as well as several spliceosomal snRNP proteins, kidney, liver and spinal cord, treatment and expression is high in several E-cadherin negative human carcinoma cell lines, &circ, «, Spinal muscular atrophy (SMA) is an autosomal recessive neurodegenerative disease characterized by loss of motor neurons in the spinal cord
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission625, 650nm/670nm
Synonyms BCD541 SMNT SMA1 SMA2 SMA3 GEMIN1 TDRD16A
Properties Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetGemin 2/SMA Conjugated
Short name Conjugated, Gemin 2/SMA Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy5
Alternative name cyanine 5 coupled, Gemin 2/SMA (Antibody to)
Alternative techniqueantibodies
Identity 11117
Gene SMN1
Long gene name survival of motor neuron 1, telomeric
Synonyms gene SMA@ SMA
Synonyms gene name Kugelberg-Welander disease) , spinal muscular atrophy (Werdnig-Hoffmann disease
Synonyms name gemin-1 tudor domain containing 16A
Locus 5q13, 2
Discovery year 1996-12-12
GenBank acession U18423
Entrez gene record 6606
Pubmed identfication 7813012
RefSeq identity NM_000344
Classification Tudor domain containing
Havana BLAST/BLAT OTTHUMG00000099361
Locus Specific Databases SMN1 - Spinal Muscular Atrophy (SMA) Leiden Muscular Dystrophy pages ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database LRG_676

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