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GGA1 Antibody

GGA1 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameGGA1 Primary Polyclonal Antibody
Also known asGGA1 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenGGA1
SpecificityThis is a highly specific antibody against GGA1
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GGA1
Gene ID number26088
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen ARF (ADP-ribosylation factor), ARF-binding proteins) are ubiquitous coat proteins that facilitate the trafficking of soluble proteins from the trans-Golgi network (TGN) to endosomes/lysosomes by means of interactions with TGN-sorting receptors, GGA1, GGA1 and GGA2 do not associate with each other, GGAs have modular structures with an N-terminal VHS (VPS-27, Hrs, Members of the GGA family, The amino-terminal VHS domains of GGAs form complexes with the cytoplasmic domains of sorting receptors by recognizing acidic-cluster di-leucine (ACLL) sequences (3), The cytosolic domain of memapsin 2, The human GGA1 gene maps to chromosome 22 and encodes a protein that shares 45% sequence identity with GGA2 and GGA3 (1), a connecting hinge segment, and STAM) domain followed by a GAT (GGA and TOM1) domain, and a C-terminal GAE (?adaptin ear) domain (5), and clathrin (1?), are multidomain proteins that bind mannose 6-phosphate receptors (MPRs) (1, binds the VHS domains of GGA1 and GGA2 (6), but not that of memapsin 1, but they do colocalize on perinuclear membranes (2), 2, 4), GGA2 (also known as VEAR) and GGA3, The GGA family of proteins (Golgi-localized
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names ADP ribosylation factor binding protein 1, ADP ribosylation factor binding protein GGA1, ADP-ribosylation factor-binding protein GGA1, ARF binding protein 1, ARF-binding protein 1, GGA 1, GGA1, GGA1 protein, GGA1_HUMAN, Gamma adaptin related protein 1, Gamma-adaptin-related protein 1, Golgi associated gamma adaptin ear containing ARF, Golgi associated gamma adaptin ear containing ARF binding protein 1, Golgi localized gamma ear containing ARF binding protein 1, Golgi-localized, OTTHUMP00000028975, OTTHUMP00000042200, gamma ear-containing, 4930406E12Rik
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetGGA1
Short nameGGA1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameGGA1 (Antibody to)
Alternative techniqueantibodies
Identity 17842
Gene GGA1
Long gene name ARF binding protein 1 , gamma adaptin ear containing, golgi associated
Locus 22q13, 1
Discovery year 2001-12-19
GenBank acession AF190862
Entrez gene record 26088
Pubmed identfication 10747088 10747089 16407204
RefSeq identity NM_013365
Classification ARF binding proteins , Golgi associated, gamma adaptin ear containing
Havana BLAST/BLAT OTTHUMG00000030985

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