Name : GGT1 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN4885716057
| Long name | GGT1 Primary Polyclonal Antibody |
| Also known as | GGT1 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | GGT1 |
| Specificity | This is a highly specific antibody against GGT1 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 380-430/569 |
| Subcellular location | Extracellular |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GGT1 |
| Gene ID number | 2678 |
| Swiss Prot | P19440 |
| Tested Applications | FCM, IF(IHC-P), IHC-P, WB |
| Recommended dilutions | FCM(1:20-100), IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | In the presence of high concentrations of dipeptides and some amino acids, Initiates extracellular glutathione (GSH) breakdown, Isoform 3 seems to be inactive, It is part of the cell antioxidant defense mechanism, The metabolism of glutathione releases free glutamate and the dipeptide, and other gamma-glutamyl compounds, can also catalyze a transpeptidation reaction, cysteinyl-glycine, glutathione conjugates, provides cells with a local cysteine supply and contributes to maintain intracellular GSH level, transferring the gamma-glutamyl moiety to an acceptor amino acid to form a new gamma-glutamyl compound, which is hydrolyzed to cysteine and glycine by dipeptidases, Cleaves the gamma-glutamyl bond of extracellular glutathione (gamma-Glu-Cys-Gly) |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | CD224, D22S672, D22S732, GGT 1, GGT1, GTG, Gamma-glutamyltransferase 1, Gamma-glutamyltranspeptidase 1, Glutathione hydrolase 1, Leukotriene-C4 hydrolase, GGT |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | GGT1 |
| Short name | GGT1 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | GGT1 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 4250 |
| Gene | GGT1 |
| Long gene name | gamma-glutamyltransferase 1 |
| Synonyms gene | GGT |
| Synonyms | D22S672 D22S732 CD224 |
| Locus | 22q11, 23 |
| Discovery year | 1986-01-01 |
| GenBank acession | M24903 |
| Entrez gene record | 2678 |
| Pubmed identfication | 8104871 18357469 |
| RefSeq identity | NM_013430 |
| Classification | Gamma-glutamyltransferases CD molecules |
| Havana BLAST/BLAT | OTTHUMG00000030859 |