Name : GGT6 Antibody, FITC Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN5924117702
| Long name | FITC Conjugated, GGT6 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Anti-FITC Antibody |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | GGT6 |
| Specificity | This is a highly specific antibody against GGT6 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human GGT6 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Belonging to the gamma-glutamyltranspeptidase family, GGT1 is released into the bloodstream after liver damage, GGT5 converts leukotriene C4 to leukotriene D4, GGT6 (gamma-glutamyltransferase 6), GGT6 exists as two alternatively spliced isoforms, In human serum and in human tissues, In humans, This enzyme is located on the outer surface of the cell membrane and is widely distributed in mammalian tissues involved in absorption and secretion, and an elevated level of the enzyme may be a useful early sign of hepatocellular carcinoma, but this heterogeneity can be attributed to different glycosylation of the same peptide rather than to the products of different genes, convert synthetic substrates that are commonly used to assay GGT, hepatic GGT activity is elevated in some liver diseases, however, is a 493 amino acid single-pass type II membrane protein that cleaves glutathione conjugates, it does not, there is a marked heterogeneity in GGT, Gamma-glutamyltranspeptidase (GGT) acts as a glutathionase and catalyzes the transfer of the glutamyl moiety of glutathione to a variety of amino acids and dipeptide acceptors |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 494nm/518nm |
| Synonyms | FLJ90165 |
| Properties | Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | GGT6 Conjugated |
| Short name | FITC Conjugated, GGT6 Antibody |
| Technique | Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | FITC |
| Alternative name | fluorecein coupled, GGT6 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 26891 |
| Gene | GGT6 |
| Long gene name | gamma-glutamyltransferase 6 |
| Synonyms gene name | gamma-glutamyltransferase 6 homolog (rat) |
| Locus | 17p13, 2 |
| Discovery year | 2005-11-14 |
| GenBank acession | AK074646 |
| Entrez gene record | 124975 |
| Pubmed identfication | 18357469 |
| RefSeq identity | NM_153338 |
| Classification | Gamma-glutamyltransferases |
| Havana BLAST/BLAT | OTTHUMG00000177827 |