| Long name | Cy5, 5 Conjugated, GHR Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Cy5, 5, 5, Cy5 |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | GHR |
| Specificity | This is a highly specific antibody against GHR |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen_range | 290-340/638 |
| Subcellular location | Cytoplasm |
| Source | KLH conjugated synthetic peptide derived from human GHR |
| Gene ID number | 2690 |
| Swiss Prot | P10912 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Pig, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Isoform 2 up-regulates the production of GHBP and acts as a negative inhibitor of GH signaling, On ligand binding, The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling, couples to the JAK2/STAT5 pathway (By similarity), Receptor for pituitary gland growth hormone involved in regulating postnatal body growth |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 675nm/694nm |
| Synonyms | GHBP |
| Properties | Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated | These antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths |
| Gene target | GHR Conjugated |
| Short name | Conjugated, GHR Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | 5, Cy5 |
| Alternative name | cyanine 5, 5 coupled, growth hormone receptor (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | GHBP, GHR and IDBG-18930 and ENSG00000112964 and 2690, GHR and IDBG-629685 and ENSBTAG00000001335 and 280805, Ghr and IDBG-127871 and ENSMUSG00000055737 and 14600, nuclei, proline-rich region binding, this GO :0000187 and activation of MAPK activity and biological process this GO :0000255 and allantoin metabolic process and biological process this GO :0004903 and growth hormone receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006101 and citrate metabolic process and biological process this GO :0006103 and 2-oxoglutarate metabolic process and biological process this GO :0006105 and succinate metabolic process and biological process this GO :0006107 and oxaloacetate metabolic process and biological process this GO :0006549 and isoleucine metabolic process and biological process this GO :0006573 and valine metabolic process and biological process this GO :0006600 and creatine metabolic process and biological process this GO :0006631 and fatty acid metabolic process and biological process this GO :0006897 and endocytosis and biological process this GO :0007259 and JAK-STAT cascade and biological process this GO :0009725 and response to hormone and biological process this GO :0009755 and hormone-mediated signaling pathway and biological process this GO :0009986 and cell surface and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0017046 and peptide hormone binding and molecular function this GO :0019221 and cytokine-mediated signaling pathway and biological process this GO :0019530 and taurine metabolic process and biological process this GO :0019838 and growth factor binding and molecular function this GO :0019898 and extrinsic component of membrane and cellular component this GO :0019901 and protein kinase binding and molecular function this GO :0019903 and protein phosphatase binding and molecular function this GO :0031623 and receptor internalization and biological process this GO :0032094 and response to food and biological process this GO :0032355 and response to estradiol and biological process this GO :0032869 and cellular response to insulin stimulus and biological process this GO :0032870 and cellular response to hormone stimulus and biological process this GO :0034097 and response to cytokine and biological process this GO :0040014 and regulation of multicellular organism growth and biological process this GO :0040018 and positive regulation of multicellular organism growth and biological process this GO :0042169 and SH2 domain binding and molecular function this GO :0042517 and positive regulation of tyrosine phosphorylation of Stat3 protein and biological process this GO :0042523 and positive regulation of tyrosine phosphorylation of Stat5 protein and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0042976 and activation of Janus kinase activity and biological process this GO :0042977 and activation of JAK2 kinase activity and biological process this GO :0043025 and neuronal cell body and cellular component this GO :0043235 and receptor complex and cellular component this GO :0043278 and response to morphine and biological process this GO :0043434 and response to peptide hormone and biological process this GO :0044236 and multicellular organismal metabolic process and biological process this GO :0045597 and positive regulation of cell differentiation and biological process this GO :0046427 and positive regulation of JAK-STAT cascade and biological process this GO :0046449 and creatinine metabolic process and biological process this GO :0046898 and response to cycloheximide and biological process this GO :0048009 and insulin-like growth factor receptor signaling pathway and biological process this GO :0050731 and positive regulation of peptidyl-tyrosine phosphorylation and biological process this GO :0051384 and response to glucocorticoid and biological process this GO :0060351 and cartilage development involved in endochondral bone morphogenesis and biological process this GO :0060396 and growth hormone receptor signaling pathway and biological process this GO :0060397 and JAK-STAT cascade involved in growth hormone signaling pathway and biological process this GO :0070064 and proline-rich region binding and molecular function this GO :0070195 and growth hormone receptor complex and cellular component this GO :0070555 and response to interleukin-1 and biological process this GO :1901215 and negative regulation of neuron death and biological process, this GO :0004903: growth hormone receptor activity, this GO :0004903: growth hormone receptor activity and also this GO :0005515: protein binding and also this GO :0017046: peptide hormone binding and also this GO :0019838: growth factor binding and also this GO :0019901: protein kinase binding and also this GO :0019903: protein phosphatase binding and also this GO :0042169: SH2 domain binding and also this GO :0042803: protein homodimerization activity and also this GO :0070064: proline-rich region binding, this GO :0005515: protein binding, this GO :0017046: peptide hormone binding, this GO :0019838: growth factor binding, this GO :0019901: protein kinase binding, this GO :0019903: protein phosphatase binding, this GO :0042169: SH2 domain binding, this GO :0042803: protein homodimerization activity, this GO :0070064: proline-rich region binding, growth hormone receptor |
| Identity | 4263 |
| Gene | GHR |
| Long gene name | growth hormone receptor |
| Synonyms name | growth hormone binding protein |
| Locus | 5p13, 1-p12 |
| Discovery year | 1989-06-30 |
| Entrez gene record | 2690 |
| RefSeq identity | NM_000163 |
| Classification | Fibronectin type III domain containing |
| Havana BLAST/BLAT | OTTHUMG00000094791 |
| Locus Specific Databases | LOVD - Leiden Open Variation Database |
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