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GHRHR Antibody

GHRHR Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameGHRHR Primary Polyclonal Antibody
Also known asGHRHR PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenGHRHR
SpecificityThis is a highly specific antibody against GHRHR
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Subcellular locationExtracellular
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GHRHR
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Binding of GHRH leads to the coupling of GHRH-R to G-protein which stimulates increased adenylyl cyclase activity and the accumulation of cAMP leading to the synthesis and release of growth hormone and somatotroph proliferation, GHRH and GHRH-R may also play a role in the regulation of non-rapid eye movement sleep (NREMS), GHRH-R plays an important role in growth and acts as a high-affinity receptor for GHRH, In addition, Mutations in the gene encoding this protein can result in isolated growth hormone deficiency (IGHD), The expression of GHRH-R is dependent on the presence of the POU domain factor Pit-1, also known as Dwarfism of Sindh, and anterior pituitary hypoplasia (APH), reproduction and immune function, this signalling pathway may have direct action in fetal/placental development, GHRH-R is a seven transmembrane domain protein that localizes to the somatotroph of the pituitary
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names GHRH R, GHRH receptor, GHRHR_HUMAN, GHRHRpsv, GRF R, GRF receptor, GRFR, Ghrhr, Growth hormone releasing factor receptor, Growth hormone releasing hormone receptor, Growth hormone-releasing factor receptor, Growth hormone-releasing hormone receptor, GHRFR
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetGHRHR
Short nameGHRHR Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameGHRHR (Antibody to)
Alternative techniqueantibodies
Identity 4266
Gene GHRHR
Long gene name growth hormone releasing hormone receptor
Locus 7p14, 3
Discovery year 1993-06-22
Entrez gene record 2692
Pubmed identfication 7680413 7514564
Classification Glucagon receptor family
Havana BLAST/BLAT OTTHUMG00000152801

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