Name : GHRHR Antibody, ALEXA FLUOR 594
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN4349463816
| Long name | ALEXA FLUOR 594 Conjugated, GHRHR Polyclonal Antibody |
| Also known as | Anti-GHRHR PAb ALEXA FLUOR 594 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 594, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | GHRHR |
| Specificity | This is a highly specific antibody against GHRHR |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Subcellular location | Extracellular |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GHRHR |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Binding of GHRH leads to the coupling of GHRH-R to G-protein which stimulates increased adenylyl cyclase activity and the accumulation of cAMP leading to the synthesis and release of growth hormone and somatotroph proliferation, GHRH and GHRH-R may also play a role in the regulation of non-rapid eye movement sleep (NREMS), GHRH-R plays an important role in growth and acts as a high-affinity receptor for GHRH, In addition, Mutations in the gene encoding this protein can result in isolated growth hormone deficiency (IGHD), The expression of GHRH-R is dependent on the presence of the POU domain factor Pit-1, also known as Dwarfism of Sindh, and anterior pituitary hypoplasia (APH), reproduction and immune function, this signalling pathway may have direct action in fetal/placental development, GHRH-R is a seven transmembrane domain protein that localizes to the somatotroph of the pituitary |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 590nm/617nm |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | 594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated | Alexa conjugate 1 |
| Gene target | GHRHR |
| Short name | GHRHR Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 594 |
| Alternative name | ALEXA FLUOR 594, GHRHR (Antibody to) |
| Alternative technique | antibodies |
| Identity | 4266 |
| Gene | GHRHR |
| Long gene name | growth hormone releasing hormone receptor |
| Locus | 7p14, 3 |
| Discovery year | 1993-06-22 |
| Entrez gene record | 2692 |
| Pubmed identfication | 7680413 7514564 |
| Classification | Glucagon receptor family |
| Havana BLAST/BLAT | OTTHUMG00000152801 |