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GHRHR Antibody, Biotin Conjugated

GHRHR Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, GHRHR Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenGHRHR
SpecificityThis is a highly specific antibody against GHRHR
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Subcellular locationExtracellular
SourceKLH conjugated synthetic peptide derived from human GHRHR
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Binding of GHRH leads to the coupling of GHRH-R to G-protein which stimulates increased adenylyl cyclase activity and the accumulation of cAMP leading to the synthesis and release of growth hormone and somatotroph proliferation, GHRH and GHRH-R may also play a role in the regulation of non-rapid eye movement sleep (NREMS), GHRH-R plays an important role in growth and acts as a high-affinity receptor for GHRH, In addition, Mutations in the gene encoding this protein can result in isolated growth hormone deficiency (IGHD), The expression of GHRH-R is dependent on the presence of the POU domain factor Pit-1, also known as Dwarfism of Sindh, and anterior pituitary hypoplasia (APH), reproduction and immune function, this signalling pathway may have direct action in fetal/placental development, GHRH-R is a seven transmembrane domain protein that localizes to the somatotroph of the pituitary
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetGHRHR Conjugated
Short name Conjugated, GHRHR Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, GHRHR (Antibody to)
Alternative techniqueantibodies
Identity 4266
Gene GHRHR
Long gene name growth hormone releasing hormone receptor
Locus 7p14, 3
Discovery year 1993-06-22
Entrez gene record 2692
Pubmed identfication 7680413 7514564
Classification Glucagon receptor family
Havana BLAST/BLAT OTTHUMG00000152801

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