Name : GLE1 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN8555259049
| Long name | GLE1 Primary Polyclonal Antibody |
| Also known as | GLE1 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | GLE1 |
| Specificity | This is a highly specific antibody against GLE1 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GLE1 |
| Gene ID number | 2733 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Defects in the gene encoding Gle1 are the cause of lethal congenital contracture syndrome type 1 (LCCS1) and lethal arthrogryposis with anterior horn cell disease (LAAHD), Expressed as two alternatively spliced isoforms, Gle1, Gle1 associates with the NPC and is required for the transport of poly(A)-containing mRNAs from the nucleus to the cytoplasm, also known as GLE1L, is a 698 amino acid protein that localizes to both the nucleus and the cytoplasm and belongs to the Gle1 family, micrognatia, multi-step process involving several cytoplasmic factors that mediate protein passage through the nuclear pore complex (NPC), pterygia and prenatal death, pulmonary hypoplasia, the former of which is characterized by early fetal hydrops and akinesia, while the latter is associated with respiratory failure, Protein transport across the nucleus is a selective |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | GLE1, GLE1 RNA export mediator homolog, GLE1 RNA export mediator like yeast, GLE1 like RNA export mediator, GLE1 like protein, GLE1-like protein, GLE1L, GLE1_HUMAN, LCCS, LCCS 1, LCCS1, Nucleoporin GLE1, hGLE1, GLE 1 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | GLE1 |
| Short name | GLE1 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | GLE1 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 4315 |
| Gene | GLE1 |
| Long gene name | GLE1, RNA export mediator |
| Synonyms gene | GLE1L LCCS1 |
| Synonyms gene name | GLE1 (yeast homolog)-like, RNA export mediator GLE1 RNA export mediator-like (yeast) GLE1 RNA export mediator (yeast) lethal congenital contracture syndrome 1 GLE1 RNA export mediator homolog (yeast) |
| Synonyms | hGLE1 |
| Locus | 9q34, 11 |
| Discovery year | 1998-06-18 |
| GenBank acession | AF058922 |
| Entrez gene record | 2733 |
| Pubmed identfication | 9618489 18204449 |
| RefSeq identity | NM_001003722 |
| Classification | Nucleoporins |
| Havana BLAST/BLAT | OTTHUMG00000020749 |
| Locus Specific Databases | LRG_484 |