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GLI2 Antibody
GLI2 Antibody size: 0.08 ml 199
Supplier
NJS POLY
Price
199
Size
0.08 ml
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| Category | Antibody |
| Concentration | pH 7, with 0, 09% sodium azide, 4, In 1X PBS |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | GLI2 |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | ELISA, FACS, IF, WB |
| Recommended dilutions | Flow Cytometry: 1:25, Immunofluorescence: 1:25, Western blot: 1:1000 |
| Notes | 1, 132 (2), 86 (4) and 168 kDa (isoform 5), 88 (3), GLI-2 exists as five alternatively spliced isoforms of 133 kDa (isoform 1), Titration of the GLI2 antibody may be required due to differences in protocols and secondary/substrate sensitivity |
| Intented use | This GLI2 antibodyis to be used only for research purposes and not for diagnostics |
| Uniprot # | P10070 |
| Purity | Antigen affinity |
| Description | Binds to the DNA sequence 5'-GAACCACCCA-3' which is part of the TRE-2S regulatory element that augments the Tax-dependent enhancer of human T-cell leukemia virus type 1, Is involved in the smoothened (SHH) signaling pathway, May play a role during embryogenesis, Acts as a transcriptional activator |
| Immunogen | This GLI2 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 1287-1321 amino acids from the C-terminal region of human GLI2 |
| Storage | Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the GLI2 antibody and store frozen at -20 deg |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | GLI2 |
| Short name | GLI2 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | GLI family zinc finger 2 (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0007224 and smoothened signaling pathway and biological process this GO :0007389 and pattern specification process and biological process this GO :0007411 and axon guidance and biological process this GO :0007418 and ventral midline development and biological process this GO :0007442 and hindgut morphogenesis and biological process this GO :0007507 and heart development and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0008283 and cell proliferation and biological process this GO :0008284 and positive regulation of cell proliferation and biological process this GO :0008589 and regulation of smoothened signaling pathway and biological process this GO :0009612 and response to mechanical stimulus and biological process this GO :0009913 and epidermal cell differentiation and biological process this GO :0009953 and dorsal/ventral pattern formation and biological process this GO :0009954 and proximal/distal pattern formation and biological process this GO :0016020 and membrane and cellular component this GO :0016607 and nuclear speck and cellular component this GO :0021508 and floor plate formation and biological process this GO :0021513 and spinal cord dorsal/ventral patterning and biological process this GO :0021517 and ventral spinal cord development and biological process this GO :0021522 and spinal cord motor neuron differentiation and biological process this GO :0021696 and cerebellar cortex morphogenesis and biological process this GO :0021775 and smoothened signaling pathway involved in ventral spinal cord interneuron specification and biological process this GO :0021776 and smoothened signaling pathway involved in spinal cord motor neuron cell fate specification and biological process this GO :0021904 and dorsal/ventral neural tube patterning and biological process this GO :0021915 and neural tube development and biological process this GO :0021938 and smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation and biological process this GO :0021965 and spinal cord ventral commissure morphogenesis and biological process this GO :0021983 and pituitary gland development and biological process this GO :0030154 and cell differentiation and biological process this GO :0030324 and lung development and biological process this GO :0030879 and mammary gland development and biological process this GO :0030902 and hindbrain development and biological process this GO :0031512 and motile primary cilium and cellular component this GO :0032331 and negative regulation of chondrocyte differentiation and biological process this GO :0033089 and positive regulation of T cell differentiation in thymus and biological process this GO :0035295 and tube development and biological process this GO :0042475 and odontogenesis of dentin-containing tooth and biological process this GO :0042733 and embryonic digit morphogenesis and biological process this GO :0043565 and sequence-specific DNA binding and molecular function this GO :0044212 and transcription regulatory region DNA binding and molecular function this GO :0045666 and positive regulation of neuron differentiation and biological process this GO :0045740 and positive regulation of DNA replication and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046872 and metal ion binding and molecular function this GO :0048566 and embryonic digestive tract development and biological process this GO :0048589 and developmental growth and biological process this GO :0048646 and anatomical structure formation involved in morphogenesis and biological process this GO :0048666 and neuron development and biological process this GO :0048754 and branching morphogenesis of an epithelial tube and biological process this GO :0048856 and anatomical structure development and biological process this GO :0060032 and notochord regression and biological process this GO :0060322 and head development and biological process this GO :0060513 and prostatic bud formation and biological process this GO :0060603 and mammary gland duct morphogenesis and biological process this GO :0060831 and smoothened signaling pathway involved in dorsal/ventral neural tube patterning and biological process this GO :0071407 and cellular response to organic cyclic compound and biological process this GO :0072372 and primary cilium and cellular component this GO :0090103 and cochlea morphogenesis and biological process this GO :0097542 and ciliary tip and cellular component, GLI2 and IDBG-642543 and ENSBTAG00000011682 and, GLI2 and IDBG-68270 and ENSG00000074047 and 2736, Gli2 and IDBG-187317 and ENSMUSG00000048402 and 14633, HPE9 and PHS2 and THP1 and THP2, metal ion binding, nuclei, this GO :0000122 and negative regulation of transcription from RNA polymerase II promoter and biological process this GO :0001501 and skeletal system development and biological process this GO :0001649 and osteoblast differentiation and biological process this GO :0001701 and in utero embryonic development and biological process this GO :0001822 and kidney development and biological process this GO :0002009 and morphogenesis of an epithelium and biological process this GO :0002062 and chondrocyte differentiation and biological process this GO :0002076 and osteoblast development and biological process this GO :0003677 and DNA binding and molecular function this GO :0003682 and chromatin binding and molecular function this GO :0003700 and sequence-specific DNA binding transcription factor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005929 and cilium and cellular component this GO :0006351 and transcription, this GO :0003677: DNA binding, this GO :0003677: DNA binding and also this GO :0003682: chromatin binding and also this GO :0003700: sequence-specific DNA binding transcription factor activity and also this GO :0005515: protein binding and also this GO :0008270: zinc ion binding and also this GO :0043565: sequence-specific DNA binding and also this GO :0044212: transcription regulatory region DNA binding and also this GO :0046872: metal ion binding, this GO :0003682: chromatin binding, this GO :0003700: sequence-specific DNA binding transcription factor activity, this GO :0005515: protein binding, this GO :0008270: zinc ion binding, this GO :0043565: sequence-specific DNA binding, this GO :0044212: transcription regulatory region DNA binding, this GO :0046872: metal ion binding, GLI family zinc finger 2 |
| Identity | 4318 |
| Gene | GLI2 |
| Long gene name | GLI family zinc finger 2 |
| Synonyms gene name | GLI-Kruppel family member GLI2 glioma-associated oncogene family zinc finger 2 |
| Synonyms | THP2 HPE9 THP1 |
| Synonyms name | tax-responsive element-2 holding protein tax helper protein 1 tax helper protein 2 |
| Locus | 2q14, 2 |
| Discovery year | 1989-05-25 |
| Entrez gene record | 2736 |
| Pubmed identfication | 2850480 9557682 |
| RefSeq identity | NM_005270 |
| Classification | Zinc fingers C2H2-type |
| Havana BLAST/BLAT | OTTHUMG00000153741 |