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Gli3 Antibody

Gli3 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameGli3 Primary Polyclonal Antibody
Also known asGli3 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenGli3
SpecificityThis is a highly specific antibody against Gli3
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Gli3
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Hedgehog has been shown to enhance the expression of the Wnt family of proteins through a signaling cascade involving the GLI transcription factors, Mutations in the ptc gene, The Drosophila segment polarity gene hedgehog (hh) encodes a secreted protein that appears to function in embryonic and imaginal disc patterning, The Wnt-1 and GLI proteins have now been placed in a signaling cascade downstream of the mammalian homologs of the Drosophila hedgehog and patched proteins, The ptc gene, also identified as a Drosophila segment polarity gene, basal cell carcinoma, encodes the transmembrane protein patched, have been correlated with the most common type of cancer, however, the expression of which is precisely regulated during embryonic development, the molecular basis for this transformation was poorly understood, which affects 750, which result in unregulated hedgehog signaling, while patched functions as a repressor opposing the effects of hedgehog, 000 individuals annually in the United States alone, It has long been known that the overexpression of either Wnt-1 or the GLI proteins results in cancer
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names DNA binding protein, GCPS, GLI Kruppel family member GLI 3, GLI Kruppel family member GLI3, GLI Kruppel family member GLI3 Greig cephalopolysyndactyly syndrome, GLI family zinc finger 3, GLI3, GLI3 C-terminally truncated form, GLI3 form of 190 kDa, GLI3 form of 83 kDa, GLI3 full length protein, GLI3-190, GLI3-83, GLI3FL, GLI3_HUMAN, Gli 3, Glioma associated oncogene family zinc finger 3, Oncogene GLI3, PAP A, PAPA, PAPA 1, PAPA1, PAPB, PHS, PPD IV, PPDIV, Transcriptional activator GLI3, Transcriptional repressor GLI3R, Zinc finger protein GLI 3, Zinc finger protein GLI3, ACLS
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetGli3
Short nameGli3 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameGLI family zinc finger 3 (Antibody to)
Alternative techniqueantibodies
Identity 4207
Gene GCPS
Long gene name GLI family zinc finger 3
Synonyms gene PHS
Synonyms gene name Greig cephalopolysyndactyly syndrome GLI-Kruppel family member GLI3 glioma-associated oncogene family zinc finger 3
Synonyms PAP-A PAPA PAPA1 PAPB ACLS PPDIV GLI3
Synonyms name zinc finger protein GLI3 oncogene GLI3 DNA-binding protein
Locus 7p14, 1
Discovery year 1989-05-29
Entrez gene record 2737
Pubmed identfication 2118997
RefSeq identity NM_000168
Classification Zinc fingers C2H2-type
Havana BLAST/BLAT OTTHUMG00000023630

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