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Gli3 Antibody, ALEXA FLUOR 647

Gli3 Antibody, ALEXA FLUOR 647 size: 100ul 332

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 332
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 647 Conjugated, Gli3 Polyclonal Antibody
Also known asAnti-Gli3 PAb ALEXA FLUOR 647
CategoryConjugated Primary Antibodies
Conjugated with 647, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenGli3
SpecificityThis is a highly specific antibody against Gli3
ModificationUnmodified
Modification SiteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Gli3
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Hedgehog has been shown to enhance the expression of the Wnt family of proteins through a signaling cascade involving the GLI transcription factors, Mutations in the ptc gene, The Drosophila segment polarity gene hedgehog (hh) encodes a secreted protein that appears to function in embryonic and imaginal disc patterning, The Wnt-1 and GLI proteins have now been placed in a signaling cascade downstream of the mammalian homologs of the Drosophila hedgehog and patched proteins, The ptc gene, also identified as a Drosophila segment polarity gene, basal cell carcinoma, encodes the transmembrane protein patched, have been correlated with the most common type of cancer, however, the expression of which is precisely regulated during embryonic development, the molecular basis for this transformation was poorly understood, which affects 750, which result in unregulated hedgehog signaling, while patched functions as a repressor opposing the effects of hedgehog, 000 individuals annually in the United States alone, It has long been known that the overexpression of either Wnt-1 or the GLI proteins results in cancer
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission650nm/665nm
Synonyms PAP-A PAPA PAPA1 PAPB ACLS PPDIV GLI3
Properties ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the Gli3 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation ALEXA FLUOR 647, Alexa Fluor
Gene targetGli3
Short nameGli3 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 647
Alternative name ALEXA FLUOR 647, GLI family zinc finger 3 (Antibody to)
Alternative techniqueantibodies
Identity 4207
Gene GCPS
Long gene name GLI family zinc finger 3
Synonyms gene PHS
Synonyms gene name Greig cephalopolysyndactyly syndrome GLI-Kruppel family member GLI3 glioma-associated oncogene family zinc finger 3
Synonyms name zinc finger protein GLI3 oncogene GLI3 DNA-binding protein
Locus 7p14, 1
Discovery year 1989-05-29
Entrez gene record 2737
Pubmed identfication 2118997
RefSeq identity NM_000168
Classification Zinc fingers C2H2-type
Havana BLAST/BLAT OTTHUMG00000023630

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