Name : Gli3 Antibody, Cy3 Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :350
SKU : GEN2391546056
| Long name | Cy3 Conjugated, Gli3 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | cy3 conjugation kit |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | Gli3 |
| Specificity | This is a highly specific antibody against Gli3 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human Gli3 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Hedgehog has been shown to enhance the expression of the Wnt family of proteins through a signaling cascade involving the GLI transcription factors, Mutations in the ptc gene, The Drosophila segment polarity gene hedgehog (hh) encodes a secreted protein that appears to function in embryonic and imaginal disc patterning, The Wnt-1 and GLI proteins have now been placed in a signaling cascade downstream of the mammalian homologs of the Drosophila hedgehog and patched proteins, The ptc gene, also identified as a Drosophila segment polarity gene, basal cell carcinoma, encodes the transmembrane protein patched, have been correlated with the most common type of cancer, however, the expression of which is precisely regulated during embryonic development, the molecular basis for this transformation was poorly understood, which affects 750, which result in unregulated hedgehog signaling, while patched functions as a repressor opposing the effects of hedgehog, 000 individuals annually in the United States alone, It has long been known that the overexpression of either Wnt-1 or the GLI proteins results in cancer |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 512, 550nm/570, 615nm |
| Synonyms | DNA binding protein, GCPS, GLI Kruppel family member GLI 3, GLI Kruppel family member GLI3, GLI Kruppel family member GLI3 Greig cephalopolysyndactyly syndrome, GLI family zinc finger 3, GLI3, GLI3 C-terminally truncated form, GLI3 form of 190 kDa, GLI3 form of 83 kDa, GLI3 full length protein, GLI3-190, GLI3-83, GLI3FL, GLI3_HUMAN, Gli 3, Glioma associated oncogene family zinc finger 3, Oncogene GLI3, PAP A, PAPA, PAPA 1, PAPA1, PAPB, PHS, PPD IV, PPDIV, Transcriptional activator GLI3, Transcriptional repressor GLI3R, Zinc finger protein GLI 3, Zinc finger protein GLI3, ACLS |
| Properties | 1 of the Gli3 Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | Gli3 Conjugated |
| Short name | Conjugated, Gli3 Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Cy3 |
| Alternative name | cyanine 3 coupled, GLI family zinc finger 3 (Antibody to) |
| Alternative technique | antibodies |