| Alternative name1 | ATF-1, ATF-2), Astrocyte-derived trophic factor 1, Glial cell line-derived neurotrophic factor, Anti-Glial Derived Neurotrophic Factor (GDNF |
| Alternative name2 | ATF-1, ATF-2), Astrocyte-derived trophic factor 1, Glial cell line-derived neurotrophic factor, Glial Derived Neurotrophic Factor (GDNF |
| Alternative name3 | ATF-1, ATF-2), Astrocyte-derived trophic factor 1, Glial cell line-derived neurotrophic factor, Glial Derived Neurotrophic Factor (GDNF |
| Alternative name4 | Glial Derived Neurotrophic Factor |
| Alternative name5 | ATF-1, ATF-2), Astrocyte-derived trophic factor 1, Glial cell line-derived neurotrophic factor, Anti -Glial Derived Neurotrophic Factor (GDNF |
| Other names | ATF, Astrocyte-derived trophic factor, Glial cell line-derived neurotrophic factor, OTTHUMP00000116024, OTTHUMP00000116025, OTTHUMP00000221304, OTTHUMP00000221305, OTTHUMP00000221306, astrocyte-derived trophic factor, glial cell derived neurotrophic factor, glial cell line derived neurotrophic factor, glial cell line-derived neurotrophic factor, hGDNF, glial derived neurotrophic factor |
| Gene name | N/A |
| Gene name synonims | N/A |
| Other gene names | ATF1, ATF2, GDNF, HFB1-GDNF, HSCR3, N/A, GDNF |
| Category | Antibodies |
| Clonality | Polyclonal |
| Immunoglobulin isotype | N/A |
| Clone | Polyclonal antibody |
| Host organism | Source: Human, Host: Sheep |
| Species reactivity | Mouse, Rat, Human |
| Specificity and cross-reactivity | Species Crossreactivity: This antibody is known to react with human, mouse and rat GDNF, No cross reativity with NTN has been observed in western blot analysis |
| Purification method | Serum |
| Form/Appearance | Centrifuge to remove any insoluble material, Reconstitute in 100ul of sterile water, Supplied as a lyophilized powder |
| Concentration | N/A |
| Storage and shipping | Aliquots are stable for at least 12 months productone should be stored at -20 degrees Celsius, For long-term storage and to avoid repeated freezing and thawing, For maximum recovery of product, Further dilutions can be made in assay buffer, aliquot For optimal long term storage, centrifuge the original vial after thawing and prior to removing the cap, productone should be kept at -20 degrees Celsius, Store at 4 degrees Celsius for short term storage |
| Tested for: | Western Blot (WB) |
| Description | Aplha, Complex subunit associated factors are involved in hybridoma growth, Eosinohils, NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells, cell lines and tissues in culture till half confluency, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation, For cells |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Gene target | ATF-1, ATF-2), Astrocyte-derived trophic factor 1, Glial line-derived neurotrophic factor, Glial Derived Neurotrophic Factor (GDNF |
| Short name | ATF-1, ATF-2), Astrocyte-derived trophic factor 1, Glial line-derived neurotrophic factor, Glial Derived Neurotrophic Factor (GDNF |
| Alternative name | ATF-1, ATF-2), Astrocyte-derived trophic factor 1, Glial cellular line-derived neurotrophic factor, Glial Derived Neurotrophic Factor (glial cell derived neurotrophic factor |
| Alternative to gene target | ATF1 and ATF2 and HFB1-GDNF and HSCR3, BT, Extracellular, GDNF and IDBG-17169 and ENSG00000168621 and 2668, Gdnf and IDBG-128378 and ENSMUSG00000022144 and 14573, protein homodimerization activity, this GO :0001656 and metanephros development and biological process this GO :0001657 and ureteric bud development and biological process this GO :0001658 and branching involved in ureteric bud morphogenesis and biological process this GO :0001755 and neural crest cell migration and biological process this GO :0001759 and organ induction and biological process this GO :0001941 and postsynaptic membrane organization and biological process this GO :0003337 and mesenchymal to epithelial transition involved in metanephros morphogenesis and biological process this GO :0005102 and receptor binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0007165 and signal transduction and biological process this GO :0007399 and nervous system development and biological process this GO :0007411 and axon guidance and biological process this GO :0007422 and peripheral nervous system development and biological process this GO :0008083 and growth factor activity and molecular function this GO :0008344 and adult locomotory behavior and biological process this GO :0021784 and postganglionic parasympathetic nervous system development and biological process this GO :0030432 and peristalsis and biological process this GO :0031175 and neuron projection development and biological process this GO :0032770 and positive regulation of monooxygenase activity and biological process this GO :0033603 and positive regulation of dopamine secretion and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043524 and negative regulation of neuron apoptotic process and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0048255 and mRNA stabilization and biological process this GO :0048484 and enteric nervous system development and biological process this GO :0048485 and sympathetic nervous system development and biological process this GO :0051584 and regulation of dopamine uptake involved in synaptic transmission and biological process this GO :0060676 and ureteric bud formation and biological process this GO :0060688 and regulation of morphogenesis of a branching structure and biological process this GO :0072107 and positive regulation of ureteric bud formation and biological process this GO :0072108 and positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis and biological process this GO :0090190 and positive regulation of branching involved in ureteric bud morphogenesis and biological process this GO :2001240 and negative regulation of extrinsic apoptotic signaling pathway in absence of ligand and biological process, this GO :0005102: receptor binding, this GO :0005102: receptor binding and also this GO :0008083: growth factor activity and also this GO :0042803: protein homodimerization activity, this GO :0008083: growth factor activity, this GO :0042803: protein homodimerization activity, 58072 and IDBG-630047 and ENSBTAG00000005176 and 386587, glial cell derived neurotrophic factor |
| Identity | 4232 |
| Gene | GDNF |
| Long gene name | glial cell derived neurotrophic factor |
| Synonyms | ATF1 ATF2 HFB1-GDNF |
| Synonyms name | astrocyte-derived trophic factor glial cell line derived neurotrophic factor glial derived neurotrophic factor |
| Locus | 5p13, 2 |
| Discovery year | 1995-05-04 |
| Entrez gene record | 2668 |
| Pubmed identfication | 8493557 |
| RefSeq identity | NM_000514 |
| Classification | Endogenous ligands |
| Havana BLAST/BLAT | OTTHUMG00000090809 |
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