Name : Gliomedin Antibody, ALEXA FLUOR 647
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN6414078511
| Long name | ALEXA FLUOR 647 Conjugated, Gliomedin Polyclonal Antibody |
| Also known as | Anti-Gliomedin PAb ALEXA FLUOR 647 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 647, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | Gliomedin |
| Specificity | This is a highly specific antibody against Gliomedin |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Subcellular location | Extracellular |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Gliomedin/COLM |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Accumulation of Na+ channels at the nodes of Ranvier is a prerequisite for saltatory conduction, Gliomedin is a glial ligand for Neurofascin and NrCAM, Gliomedin is a single-pass type II membrane protein localized to the nodes of Ranvier and is specifically expressed in spinal cord, Gliomedin is expressed by myelinating Schwann cells and accumulates at the edges of each myelin segment during development, Gliomedin is thought to play a role in the formation of the nodes of Ranvier along myelinated axons, In peripheral nerves, It is more abundant in peripheral than central nervous system, brain, clustering of these channels along the axolemma is regulated by myelinating Schwann cells through an unknown mechanism, placenta and sciatic nerve, two axonal immunoglobulin cell adhesion molecules that are associated with Na+ channels at the nodes of Ranvier, where it aligns with the forming nodes, Gliomedin is a 551 amino acid protein encoded by the human gene GLDN |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 650nm/665nm |
| Synonyms | CRG-L2 CLOM colmedin UNC-112 |
| Properties | ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the Gliomedin Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 647, Alexa Fluor |
| Gene target | Gliomedin |
| Short name | Gliomedin Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 647 |
| Alternative name | ALEXA FLUOR 647, Gliomedin (Antibody to) |
| Alternative technique | antibodies |
| Identity | 29514 |
| Gene | GLDN |
| Long gene name | gliomedin |
| Synonyms gene | COLM |
| Synonyms gene name | collomin |
| Locus | 15q21, 2 |
| Discovery year | 2004-05-18 |
| GenBank acession | AY358144 |
| Entrez gene record | 342035 |
| Pubmed identfication | 16039564 12642876 |
| RefSeq identity | NM_181789 |
| Havana BLAST/BLAT | OTTHUMG00000131746 |