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Gliomedin Antibody, Biotin Conjugated

Gliomedin Antibody, Biotin Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name Biotin Conjugated, Gliomedin Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenGliomedin
SpecificityThis is a highly specific antibody against Gliomedin
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Subcellular locationExtracellular
SourceKLH conjugated synthetic peptide derived from human Gliomedin/COLM
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Accumulation of Na+ channels at the nodes of Ranvier is a prerequisite for saltatory conduction, Gliomedin is a glial ligand for Neurofascin and NrCAM, Gliomedin is a single-pass type II membrane protein localized to the nodes of Ranvier and is specifically expressed in spinal cord, Gliomedin is expressed by myelinating Schwann cells and accumulates at the edges of each myelin segment during development, Gliomedin is thought to play a role in the formation of the nodes of Ranvier along myelinated axons, In peripheral nerves, It is more abundant in peripheral than central nervous system, brain, clustering of these channels along the axolemma is regulated by myelinating Schwann cells through an unknown mechanism, placenta and sciatic nerve, two axonal immunoglobulin cell adhesion molecules that are associated with Na+ channels at the nodes of Ranvier, where it aligns with the forming nodes, Gliomedin is a 551 amino acid protein encoded by the human gene GLDN
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms CLOM, COLM, CRG L2, Cancer related gene-Liver 2, Colm gene name, Colmedin, FLJ23917, GLDN_HUMAN, Gldn gene name, UNC 112, collomin, CANCER RELATED GENE LIVER 2
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetGliomedin Conjugated
Short name Conjugated, Gliomedin Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, Gliomedin (Antibody to)
Alternative techniqueantibodies

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