Name : GLTSCR2/PICT1 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN8690385312
| Long name | GLTSCR2/PICT1 Primary Polyclonal Antibody |
| Also known as | GLTSCR2/PICT1 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | GLTSCR2/PICT1 |
| Specificity | This is a highly specific antibody against GLTSCR2/PICT1 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GLTSCR2/PICT1 |
| Gene ID number | 29997 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Five Ser/Thr residues within the C-terminal segment of PTEN, PICT-1 also interacts with herpes simplex virus 1 regulatory proteins ICP22 and ICP0, PICT-1 is localized to the nucleus and/or nucleolus and is highly expressed in pancreas and heart, Protein interacting with PTEN carboxyl terminus 1 (PICT-1), The tumor suppressor GLTSCR2 gene, also designated p60 or Glioma tumor suppressor candidate region gene 2 protein, and maps to human chromosome 19q13, are phosphorylated upon binding of PTEN to PICT-1 and may contribute to the stabilization of PTEN, binds to the C-terminus of PTEN and regulates its turnover, but can also be detected in liver, especially oligodendrogliomas, including Ser-380, is located in a 150-kb minimal common deletion region for human gliomas, placenta and kidney, skeletal muscle, which encodes PICT-1, 3, The tumor suppressor PTEN plays an essential role in regulating signaling pathways involved in cell growth and apoptosis and is inactivated in a wide variety of tumors |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | GLTSCR2, GSCR2_HUMAN, PICT1, p60, protein interacting with carboxyl terminus 1, Glioma tumor suppressor candidate region gene 2 protein |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | GLTSCR2/PICT1 |
| Short name | GLTSCR2/PICT1 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | GLTSCR2/PICT1 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 4333 |
| Gene | GLTSCR2 |
| Long gene name | glioma tumor suppressor candidate region gene 2 |
| Synonyms | PICT-1 |
| Locus | 19q13, 33 |
| Discovery year | 2000-02-29 |
| GenBank acession | AF182076 |
| Entrez gene record | 29997 |
| Pubmed identfication | 10708517 16971513 17657248 |
| RefSeq identity | NM_015710 |
| Havana BLAST/BLAT | OTTHUMG00000183059 |