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Glucocorticoid receptor Antibody

Glucocorticoid receptor Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameGlucocorticoid receptor Antibody
Also known asGlucocorticoid receptor Antibody
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenGlucocorticoid receptor
SpecificityThis is a highly specific antibody against Glucocorticoid receptor
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range230-280/777
Subcellular location Nucleus, Cytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Glucocorticoid receptor
Gene ID number2908
Swiss ProtP04150
Tested Applications FCM, IF(IHC-P), IHC-P, WB
Recommended dilutions FCM(1:20-100), IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Affects inflammatory responses, Could act as a coactivator for STAT5-dependent transcription upon growth hormone (GH) stimulation and could reveal an essential role of hepatic GR in the control of body growth, Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE), Involved in chromatin remodeling, May play a negative role in adipogenesis through the regulation of lipolytic and antilipogenic genes expression, and as a modulator of other transcription factors, both for nuclear and mitochondrial DNA, cellular proliferation and differentiation in target tissues, Receptor for glucocorticoids (GC)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names GCCR, GCR, GCRST, GRL, Glucocorticoid receptor, NR3C1, Nuclear receptor subfamily 3 group C member 1, GR
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Description 2 or 3 and , However, In this sense, When such chemical-signals couple or bind to a receptor, a change in the electrical-activity of a cell, acetylcholine, am olfactory receptor is a protein-molecule that recognizes and responds to , an acetylcholine-receptor recognizes and responds to its endogenous-ligand, chemokinesor cytokines e, e, sometimes in pharmacology, such as enzymes, the term is also used to include other proteins that are drug-targets, they cause some form of cellular/tissue-response, transporters and ion-channels, The receptors are ligand binding factors of type 1, endogenous-chemical signals, g, g, protein-molecules , that receive chemical-signals from outside a cell
Gene targetGlucocorticoid receptor
Short nameGlucocorticoid receptor Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameGlucocorticoid receptor (Antibody to)
Alternative techniqueantibodies
Identity 4591
Gene ARHGAP35
Long gene name Rho GTPase activating protein 35
Synonyms gene GRLF1
Synonyms gene name glucocorticoid receptor DNA binding factor 1
Synonyms GRF-1 p190ARhoGAP P190A KIAA1722 p190RhoGAP
Locus 19q13, 32
Discovery year 1993-12-15
GenBank acession M73077
Entrez gene record 2909
Pubmed identfication 1894621 20675588
RefSeq identity NM_004491
Classification Rho GTPase activating proteins
Havana BLAST/BLAT OTTHUMG00000183438

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