| Long name | ALEXA FLUOR 488 Conjugated, Glucocorticoid receptor Antibody |
| Also known as | Anti-Glucocorticoid receptor PAb ALEXA FLUOR 488 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 488, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | Glucocorticoid receptor |
| Specificity | This is a highly specific antibody against Glucocorticoid receptor |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 230-280/777 |
| Subcellular location | Nucleus, Cytoplasm |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Glucocorticoid receptor |
| Gene ID Number | 2908 |
| Swiss Prot | P04150 |
| Tested applications | IF(IHC-P), FCM |
| Recommended dilutions | IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Affects inflammatory responses, Could act as a coactivator for STAT5-dependent transcription upon growth hormone (GH) stimulation and could reveal an essential role of hepatic GR in the control of body growth, Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE), Involved in chromatin remodeling, May play a negative role in adipogenesis through the regulation of lipolytic and antilipogenic genes expression, and as a modulator of other transcription factors, both for nuclear and mitochondrial DNA, cellular proliferation and differentiation in target tissues, Receptor for glucocorticoids (GC) |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 499nm/519nm |
| Synonyms | GRF-1 p190ARhoGAP P190A KIAA1722 p190RhoGAP |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the Glucocorticoid receptor Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Description | 2 or 3 and , However, In this sense, When such chemical-signals couple or bind to a receptor, a change in the electrical-activity of a cell, acetylcholine, am olfactory receptor is a protein-molecule that recognizes and responds to , an acetylcholine-receptor recognizes and responds to its endogenous-ligand, chemokinesor cytokines e, e, sometimes in pharmacology, such as enzymes, the term is also used to include other proteins that are drug-targets, they cause some form of cellular/tissue-response, transporters and ion-channels, The receptors are ligand binding factors of type 1, endogenous-chemical signals, g, g, protein-molecules , that receive chemical-signals from outside a cell |
| Gene target | Glucocorticoid receptor |
| Short name | Glucocorticoid receptor Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 488 |
| Alternative name | ALEXA FLUOR 488, Glucocorticoid receptor (Antibody to) |
| Alternative technique | antibodies |
| Identity | 4591 |
| Gene | ARHGAP35 |
| Long gene name | Rho GTPase activating protein 35 |
| Synonyms gene | GRLF1 |
| Synonyms gene name | glucocorticoid receptor DNA binding factor 1 |
| Locus | 19q13, 32 |
| Discovery year | 1993-12-15 |
| GenBank acession | M73077 |
| Entrez gene record | 2909 |
| Pubmed identfication | 1894621 20675588 |
| RefSeq identity | NM_004491 |
| Classification | Rho GTPase activating proteins |
| Havana BLAST/BLAT | OTTHUMG00000183438 |
Technique
Supplier
Species
Label
Iso Type
Host
Tissue