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Glucosidase 2 subunit beta Antibody

Glucosidase 2 subunit beta Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameGlucosidase 2 subunit beta Antibody
Also known asGlucosidase 2 subunit beta Antibody
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenGlucosidase 2 subunit beta
SpecificityThis is a highly specific antibody against Glucosidase 2 subunit beta
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Glucosidase 2 subunit beta
Gene ID number5589
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Glucosidase II is an ER-localized enzyme that contains a and b subunits (Glucosidase IIa and Glucosidase IIb) which form a defined heterodimeric complex, Glucosidase IIa is the catalyitc core of the enzyme and can function independently of the b subunit, Glucosidase IIb retains the complete complex in the ER, Glucosidase IIb was first purified from a human carcinoma cell line as a potential substrate for protein kinase C, The phosphorylated form of Glucosidase IIb is localized in the plasma membrane and is highly expressed in FGF-stimulated fibroblasts and epidermal carcinoma cells, The sequence of Glucosidase IIb encodes protein rich in glutamic and aspartic acid with a putative ER retention signal (HDEL) at the C-terminus, Through the HDEL signal at the C-terminus, Trimming of glucoses from N-linked core glycans on newly synthesized glycoproteins occurs sequentially through the action of Glucosidases I and II in the endoplasmic reticulum (ER)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names 80 Kda protein, AGE-R2, AGE-binding receptor 2, G19P1, GLU2B_HUMAN, Glucosidase 2 subunit beta, Glucosidase II beta subunit, Glucosidase II subunit beta, Hepatocystin, PCLD, PKCSH, PLD1, PRKCSH, Protein kinase C substrate, Protein kinase C substrate 60, Protein kinase C substrate 80 Kda protein, Protein kinase C substrate 80K-H, 1 kDa protein heavy chain, 80K-H protein
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetGlucosidase 2 subunit beta
Short nameGlucosidase 2 subunit beta Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameGlucosidase 2 functionnal sequence b (Antibody to)
Alternative techniqueantibodies
Identity 9411
Gene PRKCSH
Long gene name protein kinase C substrate 80K-H
Synonyms gene G19P1 PCLD PLD1
Synonyms gene name polycystic liver disease
Synonyms VASAP-60 GIIB
Synonyms name advanced glycation end-product receptor 2 glucosidase II beta subunit glucosidase 2 subunit beta hepatocystin
Locus 19p13, 2
Discovery year 1989-06-06
Entrez gene record 5589
Pubmed identfication 12529853
Classification MRH domain containing EF-hand domain containing
Havana BLAST/BLAT OTTHUMG00000182029

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