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GLUR3 Antibody, FITC Conjugated

GLUR3 Antibody, FITC Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name FITC Conjugated, GLUR3 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenGLUR3/GRIA 3
SpecificityThis is a highly specific antibody against GLUR3/GRIA 3
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range440-490/894
Subcellular locationExtracellular
SourceKLH conjugated synthetic peptide derived from human GLUR3
Gene ID number2892
Swiss ProtP42263
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, In the presence of CACNG4 or CACNG7 or CACNG8, L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system, The receptor then desensitizes rapidly and enters a transient inactive state, and thereby converts the chemical signal to an electrical impulse, characterized by the presence of bound agonist, leading to the opening of the cation channel, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate, Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms GluA3 GLURC MRX94
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetGLUR3 Conjugated
Short name FITC Conjugated, GLUR3 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, GLUR3 (Antibody to)
Alternative techniqueantibodies
Identity 4573
Gene GRIA3
Long gene name glutamate ionotropic receptor AMPA type subunit 3
Synonyms gene GLUR3
Synonyms gene name AMPA 3 , glutamate receptor, ionotrophic
Locus Xq25
Discovery year 1992-02-26
GenBank acession U10301
Entrez gene record 2892
Pubmed identfication 1319477 10644433
RefSeq identity NM_000828
Classification Glutamate ionotropic receptor AMPA type subunits X-linked mental retardation
Havana BLAST/BLAT OTTHUMG00000022685
Locus Specific Databases Mental Retardation database

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