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GM2A Antibody, Biotin Conjugated

GM2A Antibody, Biotin Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name Biotin Conjugated, GM2A Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenGM2A
SpecificityThis is a highly specific antibody against GM2A
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range160-193/193
Subcellular locationLysosome
SourceKLH conjugated synthetic peptide derived from human GM2A/SAP3
Gene ID number2760
Swiss ProtP17900
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
CrossreactivityHuman
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Binds gangliosides and stimulates ganglioside GM2 degradation, GM2A also exhibits some calcium-independent phospholipase activity (By similarity), It extracts single GM2 molecules from membranes and presents them in soluble form to beta-hexosaminidase A for cleavage of N-acetyl-D-galactosamine and conversion to GM3, It stimulates only the breakdown of ganglioside GM2 and glycolipid GA2 by beta-hexosaminidase A, The large binding pocket can accommodate several single chain phospholipids and fatty acids
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms SAP-3
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetGM2A Conjugated
Short name Conjugated, GM2A Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, GM2A (Antibody to)
Alternative techniqueantibodies
Identity 4367
Gene GM2A
Long gene name GM2 ganglioside activator
Synonyms gene name GM2 ganglioside activator protein
Synonyms name cerebroside sulfate activator protein sphingolipid activator protein 3
Locus 5q33, 1
Discovery year 1986-01-01
Entrez gene record 2760
Pubmed identfication 115863 1915857
RefSeq identity NM_000405
Havana BLAST/BLAT OTTHUMG00000130124
Locus Specific Databases GM2A Locus Database

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