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GM2A Antibody, FITC Conjugated

GM2A Antibody, FITC Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, GM2A Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenGM2A
SpecificityThis is a highly specific antibody against GM2A
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range160-193/193
Subcellular locationLysosome
SourceKLH conjugated synthetic peptide derived from human GM2A/SAP3
Gene ID number2760
Swiss ProtP17900
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
CrossreactivityHuman
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Binds gangliosides and stimulates ganglioside GM2 degradation, GM2A also exhibits some calcium-independent phospholipase activity (By similarity), It extracts single GM2 molecules from membranes and presents them in soluble form to beta-hexosaminidase A for cleavage of N-acetyl-D-galactosamine and conversion to GM3, It stimulates only the breakdown of ganglioside GM2 and glycolipid GA2 by beta-hexosaminidase A, The large binding pocket can accommodate several single chain phospholipids and fatty acids
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms SAP-3
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetGM2A Conjugated
Short name FITC Conjugated, GM2A Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, GM2A (Antibody to)
Alternative techniqueantibodies
Identity 4367
Gene GM2A
Long gene name GM2 ganglioside activator
Synonyms gene name GM2 ganglioside activator protein
Synonyms name cerebroside sulfate activator protein sphingolipid activator protein 3
Locus 5q33, 1
Discovery year 1986-01-01
Entrez gene record 2760
Pubmed identfication 115863 1915857
RefSeq identity NM_000405
Havana BLAST/BLAT OTTHUMG00000130124
Locus Specific Databases GM2A Locus Database

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