Name : GMEB2 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN2549212065
| Long name | GMEB2 Primary Polyclonal Antibody |
| Also known as | GMEB2 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | GMEB2 |
| Specificity | This is a highly specific antibody against GMEB2 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GMEB2 |
| Gene ID number | 26205 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | GMEB-2 functions as a homodimer or as a heterodimer with GMEB-1, GMEB-2 functions as an auxiliary factor required for parvovirus replication, GMEB-2 is ubiquitously expressed with preferential expression in developmentally important tissues, In addition, It localizes to the nucleus and cytoplasm and contains a SAND domain near its N-terminus and a C-terminal coiled coil structure, The formed complex specifically binds to glucocorticoid modulatory elements (GME) in the promoter region of target genes and recruits the histone acetylase CREB binding protein (CBP) during glucocorticoid signaling, This acts to increase sensitivity to low concentrations of glucocorticoids, bone marrow, placenta and fetal tissues, such as testis, GMEB-2 is a DNA-binding protein that plays a crucial role modulating transcription upon activation by steroid hormones |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | DNA binding protein p79P, DNA-binding protein p79P, GMEB 2, GMEB-2, GMEB2_HUMAN, Glucocorticoid modulatory element binding protein 2, Glucocorticoid modulatory element-binding protein 2, Gmeb2, KIAA1269, P p79, P79, P79P, Parvovirus initiation factor p79, RP4 663D7, 1, GMEB2 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | GMEB2 |
| Short name | GMEB2 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | GMEB2 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 4371 |
| Gene | GMEB2 |
| Long gene name | glucocorticoid modulatory element binding protein 2 |
| Synonyms | P79PIF KIAA1269 PIF79 |
| Locus | 20q13, 33 |
| Discovery year | 2000-03-30 |
| GenBank acession | AF173867 |
| Entrez gene record | 26205 |
| Pubmed identfication | 10523663 11743720 |
| RefSeq identity | NM_012384 |
| Havana BLAST/BLAT | OTTHUMG00000032988 |