Name : GMEB2 Antibody, ALEXA FLUOR 350
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN8063830344
| Long name | ALEXA FLUOR 350 Conjugated, GMEB2 Polyclonal Antibody |
| Also known as | Anti-GMEB2 PAb ALEXA FLUOR 350 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 350, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | GMEB2 |
| Specificity | This is a highly specific antibody against GMEB2 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GMEB2 |
| Gene ID Number | 26205 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | GMEB-2 functions as a homodimer or as a heterodimer with GMEB-1, GMEB-2 functions as an auxiliary factor required for parvovirus replication, GMEB-2 is ubiquitously expressed with preferential expression in developmentally important tissues, In addition, It localizes to the nucleus and cytoplasm and contains a SAND domain near its N-terminus and a C-terminal coiled coil structure, The formed complex specifically binds to glucocorticoid modulatory elements (GME) in the promoter region of target genes and recruits the histone acetylase CREB binding protein (CBP) during glucocorticoid signaling, This acts to increase sensitivity to low concentrations of glucocorticoids, bone marrow, placenta and fetal tissues, such as testis, GMEB-2 is a DNA-binding protein that plays a crucial role modulating transcription upon activation by steroid hormones |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 343nm/442nm |
| Synonyms | P79PIF KIAA1269 PIF79 |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 350, Alexa Fluor |
| Gene target | GMEB2 |
| Short name | GMEB2 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 350 |
| Alternative name | ALEXA FLUOR 350, GMEB2 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 4371 |
| Gene | GMEB2 |
| Long gene name | glucocorticoid modulatory element binding protein 2 |
| Locus | 20q13, 33 |
| Discovery year | 2000-03-30 |
| GenBank acession | AF173867 |
| Entrez gene record | 26205 |
| Pubmed identfication | 10523663 11743720 |
| RefSeq identity | NM_012384 |
| Havana BLAST/BLAT | OTTHUMG00000032988 |