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GMIP Antibody

GMIP Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameGMIP Primary Polyclonal Antibody
Also known asGMIP PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenGMIP
SpecificityThis is a highly specific antibody against GMIP
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GMIP
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Encoded by a gene that maps to human chromosome 19p13, GMIP (Gem-interacting protein) is a 970 amino acid protein that stimulates the GTPase activity of RhoA in vitro and in vivo, GMIP contains one phorbol-ester/DAG-type zinc finger and one Rho-GAP domain, GMIP interacts with Gem through its N-terminus and has a Rho GTPase-activating protein domain at its C-terminus, GMIP is able to inhibit RhoA function, The activation of the GTP-bound form is regulated by GTPase-activating proteins, leading to Actin cytoskeletal reorganization in vivo, leading to inactivation, which stimulate GTP hydrolysis, 11, The Rho family of GTP-binding proteins plays a role in the development of neuronal structure
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names GEM interacting protein, ARHGAP46
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetGMIP
Short nameGMIP Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameGMIP (Antibody to)
Alternative techniqueantibodies
Identity 24852
Gene GMIP
Long gene name GEM interacting protein
Synonyms ARHGAP46
Locus 19p13, 11
Discovery year 2004-07-29
GenBank acession AF132541
Entrez gene record 51291
Pubmed identfication 12093360 16086184
RefSeq identity NM_016573
Classification Rho GTPase activating proteins
Havana BLAST/BLAT OTTHUMG00000182329

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