Name : GMIP Antibody, Biotin Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN1790677916
| Long name | Biotin Conjugated, GMIP Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Biotinylated |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | GMIP |
| Specificity | This is a highly specific antibody against GMIP |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human GMIP |
| Tested applications | IHC-P, WB |
| Recommended dilutions | IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Encoded by a gene that maps to human chromosome 19p13, GMIP (Gem-interacting protein) is a 970 amino acid protein that stimulates the GTPase activity of RhoA in vitro and in vivo, GMIP contains one phorbol-ester/DAG-type zinc finger and one Rho-GAP domain, GMIP interacts with Gem through its N-terminus and has a Rho GTPase-activating protein domain at its C-terminus, GMIP is able to inhibit RhoA function, The activation of the GTP-bound form is regulated by GTPase-activating proteins, leading to Actin cytoskeletal reorganization in vivo, leading to inactivation, which stimulate GTP hydrolysis, 11, The Rho family of GTP-binding proteins plays a role in the development of neuronal structure |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | N/A |
| Synonyms | ARHGAP46 |
| Properties | Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | GMIP Conjugated |
| Short name | Conjugated, GMIP Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Biotin |
| Alternative name | biotinilated coupled, GMIP (Antibody to) |
| Alternative technique | antibodies |
| Identity | 24852 |
| Gene | GMIP |
| Long gene name | GEM interacting protein |
| Locus | 19p13, 11 |
| Discovery year | 2004-07-29 |
| GenBank acession | AF132541 |
| Entrez gene record | 51291 |
| Pubmed identfication | 12093360 16086184 |
| RefSeq identity | NM_016573 |
| Classification | Rho GTPase activating proteins |
| Havana BLAST/BLAT | OTTHUMG00000182329 |