Name : GMIP Antibody, FITC Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN3191327010
| Long name | FITC Conjugated, GMIP Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Anti-FITC Antibody |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | GMIP |
| Specificity | This is a highly specific antibody against GMIP |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human GMIP |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Encoded by a gene that maps to human chromosome 19p13, GMIP (Gem-interacting protein) is a 970 amino acid protein that stimulates the GTPase activity of RhoA in vitro and in vivo, GMIP contains one phorbol-ester/DAG-type zinc finger and one Rho-GAP domain, GMIP interacts with Gem through its N-terminus and has a Rho GTPase-activating protein domain at its C-terminus, GMIP is able to inhibit RhoA function, The activation of the GTP-bound form is regulated by GTPase-activating proteins, leading to Actin cytoskeletal reorganization in vivo, leading to inactivation, which stimulate GTP hydrolysis, 11, The Rho family of GTP-binding proteins plays a role in the development of neuronal structure |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 494nm/518nm |
| Synonyms | ARHGAP46 |
| Properties | Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | GMIP Conjugated |
| Short name | FITC Conjugated, GMIP Antibody |
| Technique | Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | FITC |
| Alternative name | fluorecein coupled, GMIP (Antibody to) |
| Alternative technique | antibodies |
| Identity | 24852 |
| Gene | GMIP |
| Long gene name | GEM interacting protein |
| Locus | 19p13, 11 |
| Discovery year | 2004-07-29 |
| GenBank acession | AF132541 |
| Entrez gene record | 51291 |
| Pubmed identfication | 12093360 16086184 |
| RefSeq identity | NM_016573 |
| Classification | Rho GTPase activating proteins |
| Havana BLAST/BLAT | OTTHUMG00000182329 |