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GNAS (559CT 16.1.3) Monoclonal Antibody

GNAS (559CT 16.1.3) Monoclonal Antibody size: 0.1ml 328

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 328
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name1, 3) Monoclonal Antibody, GNAS (559CT 16
Also known as1, 3) Monoclonal Antibody, GNAS (559CT 16
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenGNAS
SpecificityThis is a highly specific antibody against GNAS
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityMonoclonal
Clone number1, 3, 559CT 16
SourceThis GNAS antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 287-315 amino acids from human GNAS
Swiss ProtQ5FWY2
Tested ApplicationsWB
Recommended dilutionsWB(1:300)
Cross reactivityMouse
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Albright hereditary osteodystrophy, Alternative splicing of downstream exons of the GNAS gene is observed, McCune-Albright syndrome, Multiple transcript variants have been found for this gene, Mutations in this gene result in pseudohypoparathyroidism type 1a, The Gs protein is involved in hormonal regulation of adenylate cyclase: it activates the cyclase in response to beta-adrenergic stimuli, a key element of the classical signal transduction pathway linking receptor-ligand interactions with the activation of adenylyl cyclase and a variety of cellular reponses, and some pituitary tumors, but the full-length nature and/or biological validity of some variants have not been determined, polyostotic fibrous dysplasia of bone, progressive osseus heteroplasia, pseudohypoparathyroidism type 1b, pseudopseudohypoparathyroidism, which results in different forms of the stimulatory G protein alpha subunit, Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems
Purification method09% (W/V) sodium azide, Mouse monoclonal antibody supplied in crude ascites with 0
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
About Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones
Gene target1, 3) Monoclonal, GNAS (559CT 16
Short name1, 3) Monoclonal Antibody, GNAS (559CT 16
Technique Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody
Alternative name1, 3) monoclonal (Antibody to), GNAS (559CT 16
Alternative techniqueantibodies
Identity 4392
Gene GNAS
Long gene name GNAS complex locus
Synonyms gene GNAS1
Synonyms gene name alpha stimulating activity polypeptide 1 , guanine nucleotide binding protein (G protein)
Synonyms NESP55 NESP GNASXL GPSA SCG6 SgVI
Synonyms name secretogranin VI G protein subunit alpha S
Locus 20q13, 32
Discovery year 1990-06-29
GenBank acession M21142
Entrez gene record 2778
RefSeq identity NM_000516
Classification Granins
Havana BLAST/BLAT OTTHUMG00000033069
Locus Specific Databases LOVD - Leiden Open Variation Database

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