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GNAS Antibody

GNAS Antibody size: 0.4 ml 406

Supplier NJS POLY
Price 406
Size 0.4 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenGNAS
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, FACS, IF, IHC, WB
Recommended dilutionsFlow Cytometry: 1:10-1:50, IHC (Paraffin): 1:10-1:50, Immunofluorescence: 1:10-1:50, Western blot: 1:1000
NotesTitration of the GNAS antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis GNAS antibodyis to be used only for research purposes and not for diagnostics
Uniprot #Q5FWY2
PurityAntigen affinity
Description Albright hereditary osteodystrophy, Alternative splicing of downstream exons of the GNAS gene is observed, McCune-Albright syndrome, Multiple transcript variants have been found for this gene, Mutations in this gene result in pseudohypoparathyroidism type 1a, The Gs protein is involved in hormonal regulation of adenylate cyclase: it activates the cyclase in response to beta-adrenergic stimuli, a key element of the classical signal transduction pathway linking receptor-ligand interactions with the activation of adenylyl cyclase and a variety of cellular reponses, and some pituitary tumors, but the full-length nature and/or biological validity of some variants have not been determined, polyostotic fibrous dysplasia of bone, progressive osseus heteroplasia, pseudohypoparathyroidism type 1b, pseudopseudohypoparathyroidism, which results in different forms of the stimulatory G protein alpha subunit, Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems
ImmunogenA portion of amino acids 287-315 from the human protein was used as the immunogen for this GNAS antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the GNAS antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetGNAS
Short nameGNAS Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameGNAS (Antibody to)
Alternative techniqueantibodies
Identity 4392
Gene GNAS
Long gene name GNAS complex locus
Synonyms gene GNAS1
Synonyms gene name alpha stimulating activity polypeptide 1 , guanine nucleotide binding protein (G protein)
Synonyms NESP55 NESP GNASXL GPSA SCG6 SgVI
Synonyms name secretogranin VI G protein subunit alpha S
Locus 20q13, 32
Discovery year 1990-06-29
GenBank acession M21142
Entrez gene record 2778
RefSeq identity NM_000516
Classification Granins
Havana BLAST/BLAT OTTHUMG00000033069
Locus Specific Databases LOVD - Leiden Open Variation Database

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