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GNRHR2 Antibody

GNRHR2 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameGNRHR2 Primary Polyclonal Antibody
Also known asGNRHR2 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenGNRHR2
SpecificityThis is a highly specific antibody against GNRHR2
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Subcellular locationExtracellular
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GNRHR2
Tested Applications FCM, IF(IHC-P), IHC-P, WB
Recommended dilutions FCM(1:20-100), IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivityHuman
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Due to alternative splicing events, GnRHR2 is expressed as two isoforms, GnRHR2 is thought to have potent antiproliferative effects on ovarian and endometrial cancer cells, GnRHR2 mediates its own receptor activity via association with G proteins, Localized to the cell membrane, This hypothalamic hormone is transported to the pituitary, suggesting a possible role in tumor suppression, thereby activating a phosphatidylinositol-calcium second messenger system that regulates GnRHR2 function, where it binds to specific receptors and regulates the synthesis and release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), Gonadotropin-releasing hormone (GnRH) is released in a pulsatile manner that varies with the reproductive cycle
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names GNRR2_HUMAN, GnRH-II-R, Putative gonadotropin-releasing hormone II receptor, Type II GnRH receptor, gonadotropin-releasing hormone type 2 receptor 2, GnRH IIR
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetGNRHR2
Short nameGNRHR2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameGNRHR2 (Antibody to)
Alternative techniqueantibodies
Identity 16341
Gene GNRHR2
Long gene name gonadotropin releasing hormone receptor 2 (pseudogene)
Synonyms gene name gonadotropin-releasing hormone (type 2) receptor 2
Locus 1q21, 1
Discovery year 2001-09-26
GenBank acession AF403014
Entrez gene record 114814
Pubmed identfication 11707068
RefSeq identity NR_002328
Classification Gonadotropin releasing hormone receptors
Havana BLAST/BLAT OTTHUMG00000013742

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