Name : GNRHR2 Antibody, Cy5.5 Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :350
SKU : GEN4399436216
| Long name | Cy5, 5 Conjugated, GNRHR2 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Cy5, 5, 5, Cy5 |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | GNRHR2 |
| Specificity | This is a highly specific antibody against GNRHR2 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Subcellular location | Extracellular |
| Source | KLH conjugated synthetic peptide derived from human GNRHR2 |
| Tested applications | IF(IHC-P), FCM |
| Recommended dilutions | IF(IHC-P)(1:50-200), FCM(1:20-100) |
| Crossreactivity | Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Due to alternative splicing events, GnRHR2 is expressed as two isoforms, GnRHR2 is thought to have potent antiproliferative effects on ovarian and endometrial cancer cells, GnRHR2 mediates its own receptor activity via association with G proteins, Localized to the cell membrane, This hypothalamic hormone is transported to the pituitary, suggesting a possible role in tumor suppression, thereby activating a phosphatidylinositol-calcium second messenger system that regulates GnRHR2 function, where it binds to specific receptors and regulates the synthesis and release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), Gonadotropin-releasing hormone (GnRH) is released in a pulsatile manner that varies with the reproductive cycle |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 675nm/694nm |
| Properties | Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Conjugated | These antibodies are excite for emission at 678nm and detected at a 694 , nm wavelengths |
| Gene target | GNRHR2 Conjugated |
| Short name | Conjugated, GNRHR2 Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | 5, Cy5 |
| Alternative name | cyanine 5, 5 coupled, GNRHR2 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 16341 |
| Gene | GNRHR2 |
| Long gene name | gonadotropin releasing hormone receptor 2 (pseudogene) |
| Synonyms gene name | gonadotropin-releasing hormone (type 2) receptor 2 |
| Locus | 1q21, 1 |
| Discovery year | 2001-09-26 |
| GenBank acession | AF403014 |
| Entrez gene record | 114814 |
| Pubmed identfication | 11707068 |
| RefSeq identity | NR_002328 |
| Classification | Gonadotropin releasing hormone receptors |
| Havana BLAST/BLAT | OTTHUMG00000013742 |