Filters

GNRHR2 Antibody, FITC Conjugated

GNRHR2 Antibody, FITC Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name FITC Conjugated, GNRHR2 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenGNRHR2
SpecificityThis is a highly specific antibody against GNRHR2
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Subcellular locationExtracellular
SourceKLH conjugated synthetic peptide derived from human GNRHR2
Tested applications IF(IHC-P), FCM
Recommended dilutions IF(IHC-P)(1:50-200), FCM(1:20-100)
CrossreactivityHuman
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Due to alternative splicing events, GnRHR2 is expressed as two isoforms, GnRHR2 is thought to have potent antiproliferative effects on ovarian and endometrial cancer cells, GnRHR2 mediates its own receptor activity via association with G proteins, Localized to the cell membrane, This hypothalamic hormone is transported to the pituitary, suggesting a possible role in tumor suppression, thereby activating a phosphatidylinositol-calcium second messenger system that regulates GnRHR2 function, where it binds to specific receptors and regulates the synthesis and release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH), Gonadotropin-releasing hormone (GnRH) is released in a pulsatile manner that varies with the reproductive cycle
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetGNRHR2 Conjugated
Short name FITC Conjugated, GNRHR2 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, GNRHR2 (Antibody to)
Alternative techniqueantibodies
Identity 16341
Gene GNRHR2
Long gene name gonadotropin releasing hormone receptor 2 (pseudogene)
Synonyms gene name gonadotropin-releasing hormone (type 2) receptor 2
Locus 1q21, 1
Discovery year 2001-09-26
GenBank acession AF403014
Entrez gene record 114814
Pubmed identfication 11707068
RefSeq identity NR_002328
Classification Gonadotropin releasing hormone receptors
Havana BLAST/BLAT OTTHUMG00000013742

Subscribe to our Newsletter