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GNS/Glucosamine 6 sulfatase Antibody, Biotin Conjugated

GNS/Glucosamine 6 sulfatase Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, GNS/Glucosamine 6 sulfatase Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenGNS/Glucosamine 6 sulfatase
SpecificityThis is a highly specific antibody against GNS/Glucosamine 6 sulfatase
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human GNS/Glucosamine 6 sulfatase
Gene ID number2799
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background A member of the sulfatase family, GNS assists in the catabolism of heparin, GNS deficiency results in an autosomal recessive lysosomal storage disorder known as mucopolysaccharidosis type IIID (Sanfilippo D syndrome), GNS is encoded by a gene mapping to human chromosome 12q14, Subject to post-translational internal peptidase cleavage, and binds calcium as a cofactor, which is characterized by mild somatic disease and severe degeneration of the central nervous system, 2 and mouse chromosome 10 D2, GNS is a 552 amino acid lysosomal enzyme that hydrolyzes the 6-sulfate groups of the N-acetyl-D-glucosamine 6-sulfate units of keratan sulfate and heparan sulfate
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetGNS/Glucosamine 6 sulfatase Conjugated
Short name Conjugated, GNS/Glucosamine 6 sulfatase Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, GNS/Glucosamine 6 sulfatase (Antibody to)
Alternative techniqueantibodies
Identity 4422
Gene GNS
Long gene name glucosamine (N-acetyl)-6-sulfatase
Synonyms name Sanfilippo disease IIID N-acetylglucosamine-6-sulfatase
Locus 12q14, 3
Discovery year 1988-06-09
Entrez gene record 2799
Classification Sulfatases
Havana BLAST/BLAT OTTHUMG00000168819

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