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GOAT ANTI Bcl-2 (N-TERMINAL) Antibody

GOAT ANTI Bcl-2 (N-TERMINAL) Antibody size: 100ug 608

Supplier MBS POLYCLONALS 1
Price 608
Size 100ug
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Alternative name1Anti-GOAT ANTI Bcl-2 (N-TERMINAL)
Alternative name2Caprine ANTI Bcl-2 (N-TERMINAL)
Alternative name3Caprinae ANTI Bcl-2 (N-TERMINAL)
Alternative name4Bcl-2
Alternative name5N/A
Other names Apoptosis regulator Bcl-2, B-cell CLL/lymphoma 2, N/A, apoptosis regulator Bcl-2, protein phosphatase 1, regulatory subunit 50, apoptosis regulator Bcl-2 alpha isoform
Gene nameBcl-2
Gene name synonimsN/A
Other gene names BCL2, Bcl-2, N/A, PPP1R50, BCL2
CategoryAntibodies
ClonalityPolyclonal
Immunoglobulin isotypePolyclonal IgG
ClonePolyclonal antibody
Host organismGoat
Species reactivityHuman
Specificity and cross-reactivity Bcl-2 is antiproliferative by facilitating G<, Bcl-2 mutations have also been found in Non-Hodgkin Lymphomas, Bcl-2 regulates cell death by controlling the mitochondrial membrane permeability, It inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (apaf-1), a 25kD integral outer mitochondrial membrane protein that blocks apoptotic death in a variety of cell systems, also known as type II chronic lymphatic leukaemia, entry, /sub>, 0<, Bcl-2 This item detects an epitope within the N-terminal (NT) region of Bcl-2, _x000D__x000D_Constitutive expression of Bcl-2 is thought to be the cause of follicular lymphoma, sub>
Purification methodN/A
Form/AppearancePurified (Purified IgG - liquid)
ConcentrationIgG concentration 500ug/1000ul
Storage and shipping Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius
Tested for: ELISA (EIA), Western Blot (WB)
Description Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24°
Gene targetBcl-2
Short nameGOAT ANTI Bcl-2 (N-TERMINAL) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namecaprine antibody to Bcl-2 (N-TERMINAL) (Antibody to)
Alternative techniqueantibodies
Identity 990
Gene BCL2
Long gene name BCL2, apoptosis regulator
Synonyms gene name B-cell CLL/lymphoma 2
Synonyms Bcl-2 PPP1R50
Synonyms name protein phosphatase 1, regulatory subunit 50
Locus 18q21, 33
Discovery year 2001-06-22
GenBank acession M14745
Entrez gene record 596
RefSeq identity NM_000633 NM_000657
Classification Protein phosphatase 1 regulatory subunits BCL2 family
Havana BLAST/BLAT OTTHUMG00000132791
Locus Specific Databases LRG_1113

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