GOAT ANTI HUMAN APH-1A Antibody

GOAT ANTI HUMAN APH-1A Antibody size: 100ug 597

Price 597

Size 100ug

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Alternative name1	Anti-GOAT ANTI HUMAN APH-1A
Alternative name2	Caprine ANTI HUMAN APH-1A
Alternative name3	Caprinae ANTI Homo sapiens APH-1A
Alternative name4	APH-1A
Alternative name5	N/A
Other names	Aph-1alpha, Gamma-secretase subunit APH-1A, Presenilin-stabilization factor, anterior pharynx defective 1 homolog A (C, aph-1alpha, elegans), gamma-secretase subunit APH-1A, presenilin-stabilization factor, gamma-secretase subunit APH-1A isoform 1
Gene name	APH-1A
Gene name synonims	N/A
Other gene names	6530402N02Rik, APH-1, APH-1A, APH-1a, APH1A, CGI-78, PSF, APH1A
Category	Antibodies
Clonality	Polyclonal
Immunoglobulin isotype	Polyclonal IgG
Clone	Polyclonal antibody
Host organism	Goat
Species reactivity	Human
Specificity and cross-reactivity	_x000D_, _x000D__x000D_The gamma-secretase complex, an integral transmembrane protein, and Pen-2 (PEN2), and is an essential component of the endoprotease gamma-secretase complex, and member of the APH-1 family, by catalyzing the intramembrane S3 cleavage of ligand-activated Notch receptor proteins (Notch1-4), consisting of APH-1 (APH-1A or APH-1B), nicastrin (NCSTN), otherwise known as anterior pharynx defective 1 homolog A, plays a vital role in the evolutionarily conserved Notch signaling pathway, presenilin-1 or -2 (PSEN1 or PSEN2), resulting in the generation and release of an activated NICD fragment, which is predominantly located in the endoplasmic reticulum and cis-Golgi, which then translocates to the nucleus and activates the transcription of downstream effector genes, APH-1A This item specifically recognises human APH-1A (gamma-secretase subunit APH-1A)
Purification method	N/A
Form/Appearance	Purified (Purified IgG - liquid)
Concentration	IgG concentration 500ug/1000ul
Storage and shipping	Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius
Tested for:	ELISA (EIA), Western Blot (WB)
Description	Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against
Advisory	For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged
Properties	C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24°
Gene target	APH-1A
Short name	GOAT ANTI HUMAN APH-1A Antibody
Technique	antibodies against human proteins, antibodies for, Antibody
Alternative name	sapiens APH-1A (Antibody to), caprine antibody to H
Alternative technique	antibodies
Identity	29509
Gene	APH1A
Long gene name	aph-1 homolog A, gamma-secretase subunit
Synonyms gene name	anterior pharynx defective 1 homolog A (C, elegans) APH1A gamma secretase subunit
Synonyms	APH-1A CGI-78
Locus	1q21, 2
Discovery year	2005-02-08
GenBank acession	AF151835
Entrez gene record	51107
Pubmed identfication	10810093 12110170
RefSeq identity	NM_016022
Havana BLAST/BLAT	OTTHUMG00000012545

GOAT ANTI HUMAN APH-1A Antibody

GOAT ANTI HUMAN APH-1A Antibody size: 100ug 597

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