| Alternative name1 | Anti-GOAT ANTI HUMAN BID (C-TERMINAL) |
| Alternative name2 | Caprine ANTI HUMAN BID (C-TERMINAL) |
| Alternative name3 | Caprinae ANTI Homo sapiens BID (C-TERMINAL) |
| Alternative name4 | BID |
| Alternative name5 | N/A |
| Other names | Alternative name(s):, Alternative name(s):, Alternative name(s):, BH3 interacting domain death agonist, BH3-interacting domain death agonist, BH3-interacting domain death agonist, BID isoform ES(1b), BID isoform L(2), BID isoform Si6, BIDCleaved into the following 3 chains:BH3-interacting domain death agonist p15, Human BID coding sequence, apoptic death agonist, desmocollin type 4, p11 BID, p13 BIDBH3-interacting domain death agonist p11, p15 BIDBH3-interacting domain death agonist p13, p22 BID, p22 BID, BH3-interacting domain death agonist isoform 2 |
| Gene name | BID |
| Gene name synonims | N/A |
| Other gene names | BID, BID, FP497, BID |
| Category | Antibodies |
| Clonality | Polyclonal |
| Immunoglobulin isotype | Polyclonal IgG |
| Clone | Polyclonal antibody |
| Host organism | Goat |
| Species reactivity | Human |
| Specificity and cross-reactivity | BID is susceptible to proteolytic cleavage by caspases, Deletion of BID inhibits carcinogenesis in the liver, Granzyme B and cathepsins, Protease-cleaved BID translocates to mitochondria where it results in cytochrome c release, This constitutes the activation of the mitochondria death pathway (the intrinsic pathway) by the death stimuli, _x000D__x000D_BID contains a BH3 domain, _x000D__x000D_BID has been shown to promote cell cycle progression into S phase, a death agonist that heterodimerizes with other members of the Bcl-2 family of cell death regulators, and promotes tumorigenesis in the myeloid cells, calpains, including the agonist BAX or antagonist BCL2, leading to caspase activation and cell death, which is required for its interaction with the Bcl-2 family proteins and for its pro-death activity, whilst BID could be also involved in the maintenance of genomic stability by engaging at mitosis checkpoint, BID This item detects an epitope within the C-terminus of BID |
| Purification method | N/A |
| Form/Appearance | Purified (Purified IgG - liquid) |
| Concentration | IgG concentration 500ug/1000ul |
| Storage and shipping | Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius |
| Tested for: | ELISA (EIA), Western Blot (WB) |
| Description | Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target | BID |
| Short name | GOAT ANTI HUMAN BID (C-TERMINAL) Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | sapiens BH3 interacting domain death a this GO nist (C-TERMINAL) (Antibody to), caprine antibody to H |
| Alternative technique | antibodies |
| Alternative to gene target | BID and IDBG-1050 and ENSG00000015475 and 101929618, BID and IDBG-641320 and ENSBTAG00000013988 and 510373, Bid and IDBG-184076 and ENSMUSG00000004446 and 12122, FP497, Plasma membranes, this GO :0001836 and release of cytochrome c from mitochondria and biological process this GO :0005123 and death receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005739 and mitochondrion and cellular component this GO :0005741 and mitochondrial outer membrane and cellular component this GO :0005829 and cytosol and cellular component this GO :0006626 and protein targeting to mitochondrion and biological process this GO :0006915 and apoptotic process and biological process this GO :0006919 and activation of cysteine-type endopeptidase activity involved in apoptotic process and biological process this GO :0007420 and brain development and biological process this GO :0008625 and extrinsic apoptotic signaling pathway via death domain receptors and biological process this GO :0008637 and apoptotic mitochondrial changes and biological process this GO :0016020 and membrane and cellular component this GO :0031625 and ubiquitin protein ligase binding and molecular function this GO :0032355 and response to estradiol and biological process this GO :0032459 and regulation of protein oli this GO merization and biological process this GO :0032461 and positive regulation of protein oli this GO merization and biological process this GO :0032464 and positive regulation of protein homooli this GO merization and biological process this GO :0032592 and integral component of mitochondrial membrane and cellular component this GO :0034349 and glial cell apoptotic process and biological process this GO :0042127 and regulation of cell proliferation and biological process this GO :0042770 and signal transduction in response to DNA damage and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0045087 and innate immune response and biological process this GO :0051260 and protein homooli this GO merization and biological process this GO :0051402 and neuron apoptotic process and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0090150 and establishment of protein localization to membrane and biological process this GO :0090200 and positive regulation of release of cytochrome c from mitochondria and biological process this GO :0097191 and extrinsic apoptotic signaling pathway and biological process this GO :0097193 and intrinsic apoptotic signaling pathway and biological process this GO :1900740 and positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway and biological process this GO :1901030 and positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway and biological process this GO :1902108 and regulation of mitochondrial membrane permeability involved in apoptotic process and biological process this GO :2000045 and regulation of G1/S transition of mitotic cell cycle and biological process this GO :2001238 and positive regulation of extrinsic apoptotic signaling pathway and biological process this GO :2001244 and positive regulation of intrinsic apoptotic signaling pathway and biological process, this GO :0005123: death receptor binding, this GO :0005123: death receptor binding and also this GO :0005515: protein binding and also this GO :0031625: ubiquitin protein ligase binding, this GO :0005515: protein binding, this GO :0031625: ubiquitin protein ligase binding, ubiquitin protein ligase binding, 637, 782484, BH3 interacting domain death a this GO nist |
| Identity | 1050 |
| Gene | BID |
| Long gene name | BH3 interacting domain death agonist |
| Locus | 22q11, 21 |
| Discovery year | 1998-04-20 |
| GenBank acession | AF042083 |
| Entrez gene record | 637 |
| Pubmed identfication | 8918887 9721221 |
| RefSeq identity | NM_197966 |
| Classification | Endogenous ligands BCL2 homology region 3 (BH3) only |
| Havana BLAST/BLAT | OTTHUMG00000150087 |
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