Name : GOAT ANTI HUMAN CD14 Antibody
Supplier : MBS POLYCLONALS 1
Price :597
SKU : GEN7333367018
| Alternative name1 | Anti-GOAT ANTI HUMAN CD14 |
| Alternative name2 | Caprine ANTI HUMAN CD14 |
| Alternative name3 | Caprinae ANTI Homo sapiens CD14 |
| Alternative name4 | CD14 |
| Alternative name5 | N/A |
| Other names | CD14 molecule, Monocyte differentiation antigen CD14, Myeloid cell-specific leucine-rich glycoprotein, monocyte differentiation antigen CD14, myeloid cell-specific leucine-rich glycoprotein, monocyte differentiation antigen CD14 |
| Gene name | CD14 |
| Gene name synonims | N/A |
| Other gene names | CD14, N/A, N/A, CD14 |
| Category | Antibodies |
| Clonality | Polyclonal |
| Immunoglobulin isotype | Polyclonal IgG |
| Clone | Polyclonal antibody |
| Host organism | Goat |
| Species reactivity | Human |
| Specificity and cross-reactivity | Activation of the LPS receptor leads to NF-kappa-B activation, CD14 acts as a multiligand pattern recognition receptor, CD14 also up-regulates cell surface molecules, Upon binding of various ligands, _x000D__x000D_The LPS receptor is expressed strongly on the surface of monocytes and weakly on the surface of granulocytes, a 55kD receptor for endotoxin and other bacterial cell wall components, and has been shown to bind apoptotic cells, and is also expressed by most tissue macrophages, cytokine secretion and the inflammatory response, including MD-2 and TLR4 as part of the lipopolysaccharide (LPS) receptor, including adhesion molecules, inducing specific coassembly of additional receptors, CD14 This product detects an epitope within the internal region of CD14 |
| Purification method | N/A |
| Form/Appearance | Purified (Purified IgG - liquid) |
| Concentration | 5 mg/ml, IgG concentration 0 |
| Storage and shipping | Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius |
| Tested for: | ELISA (EIA), Immunohistology - Paraffin (IHC), Western Blot (WB) |
| Description | Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target | CD14 |
| Short name | GOAT ANTI HUMAN CD14 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | sapiens CD14 molecule (Antibody to), caprine antibody to H |
| Alternative technique | antibodies |
| Alternative to gene target | CD14 and IDBG-49157 and ENSG00000170458 and 929, CD14 and IDBG-646064 and ENSBTAG00000015032 and 281048, Cd14 and IDBG-138525 and ENSMUSG00000051439 and 12475, Extracellular, lipoteichoic acid binding, this GO :0001530 and lipopolysaccharide binding and molecular function this GO :0001847 and opsonin receptor activity and molecular function this GO :0002224 and toll-like receptor signaling pathway and biological process this GO :0002237 and response to molecule of bacterial origin and biological process this GO :0002755 and MyD88-dependent toll-like receptor signaling pathway and biological process this GO :0002756 and MyD88-independent toll-like receptor signaling pathway and biological process this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006909 and pha this GO cytosis and biological process this GO :0006915 and apoptotic process and biological process this GO :0006954 and inflammatory response and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007249 and I-kappaB kinase/NF-kappaB signaling and biological process this GO :0009408 and response to heat and biological process this GO :0009986 and cell surface and cellular component this GO :0010008 and endosome membrane and cellular component this GO :0016019 and peptidoglycan receptor activity and molecular function this GO :0031225 and anchored component of membrane and cellular component this GO :0032026 and response to magnesium ion and biological process this GO :0032496 and response to lipopolysaccharide and biological process this GO :0032760 and positive regulation of tumor necrosis factor production and biological process this GO :0034134 and toll-like receptor 2 signaling pathway and biological process this GO :0034138 and toll-like receptor 3 signaling pathway and biological process this GO :0034142 and toll-like receptor 4 signaling pathway and biological process this GO :0034612 and response to tumor necrosis factor and biological process this GO :0035666 and TRIF-dependent toll-like receptor signaling pathway and biological process this GO :0038123 and toll-like receptor TLR1:TLR2 signaling pathway and biological process this GO :0038124 and toll-like receptor TLR6:TLR2 signaling pathway and biological process this GO :0045087 and innate immune response and biological process this GO :0045121 and membrane raft and cellular component this GO :0045471 and response to ethanol and biological process this GO :0045807 and positive regulation of endocytosis and biological process this GO :0050715 and positive regulation of cytokine secretion and biological process this GO :0051602 and response to electrical stimulus and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0070891 and lipoteichoic acid binding and molecular function this GO :0071222 and cellular response to lipopolysaccharide and biological process this GO :0071223 and cellular response to lipoteichoic acid and biological process, this GO :0001530: lipopolysaccharide binding, this GO :0001530: lipopolysaccharide binding and also this GO :0001847: opsonin receptor activity and also this GO :0005515: protein binding and also this GO :0016019: peptidoglycan receptor activity and also this GO :0070891: lipoteichoic acid binding, this GO :0001847: opsonin receptor activity, this GO :0005515: protein binding, this GO :0016019: peptidoglycan receptor activity, this GO :0070891: lipoteichoic acid binding, CD14 molecule |
| Identity | 1628 |
| Gene | CD14 |
| Long gene name | CD14 molecule |
| Synonyms gene name | CD14 antigen |
| Locus | 5q31, 3 |
| Discovery year | 1988-05-31 |
| Entrez gene record | 929 |
| Pubmed identfication | 2472171 2462937 |
| RefSeq identity | NM_000591 |
| Classification | CD molecules Scavenger receptors |
| Havana BLAST/BLAT | OTTHUMG00000129507 |