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GOAT ANTI HUMAN LNK (N-TERMINAL) Antibody

GOAT ANTI HUMAN LNK (N-TERMINAL) Antibody size: 100ug 580

Supplier MBS POLYCLONALS 1
Price 580
Size 100ug
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Alternative name1Anti-GOAT ANTI HUMAN LNK (N-TERMINAL)
Alternative name2Caprine ANTI HUMAN LNK (N-TERMINAL)
Alternative name3Caprinae ANTI Homo sapiens LNK (N-TERMINAL)
Alternative name4LNK
Alternative name5N/A
Other names Lymphocyte adapter protein, Lymphocyte-specific adapter protein Lnk, SH2B adapter protein 3, SH2B adapter protein 3, SH2B adaptor protein 3, Signal transduction protein Lnk, lymphocyte-specific adapter protein Lnk, signal transduction protein Lnk, SH2B adapter protein 3
Gene nameLNK
Gene name synonimsN/A
Other gene names IDDM20, LNK, LNK, SH2B3, SH2B3
CategoryAntibodies
ClonalityPolyclonal
Immunoglobulin isotypePolyclonal IgG
ClonePolyclonal antibody
Host organismGoat
Species reactivityHuman
Specificity and cross-reactivity The role of LNK as a negative regulator, _x000D__x000D_LNK mRNA is preferentially expressed in lymph node and spleen lymphocytes and the expression of LNK in vascular endothelial cells (ECs), an SH2-containing adaptor protein, and negative regulation of Thrombopoietin-mediated cell proliferation and endomitosis in hematopoietic cell lines, and plays an essential role in B cell lymphopoiesis, includes the down regulation of the pro-inflammatory molecules VCAM-1 and E-selectin induced by TNF?, increases in response to TNF?, modulation of P13-kinase and MAPK ERK1/2 activity, which regulates cytokine receptor-mediated and growth factor pathways, <, LNK This item recognises an epitope within the N-terminal region (NT) of lymphocyte adaptor protein (LNK), _x000D_, br /
Purification methodN/A
Form/AppearancePurified (Purified IgG - liquid)
ConcentrationIgG concentration 500ug/1000ul
Storage and shipping Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius
Tested for:Western Blot (WB)
Description Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against
Advisory For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24°
Gene targetLNK
Short nameGOAT ANTI HUMAN LNK (N-TERMINAL) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative name sapiens LNK (N-TERMINAL) (Antibody to), caprine antibody to H
Alternative techniqueantibodies
Identity 29605
Gene SH2B3
Long gene name SH2B adaptor protein 3
Synonyms LNK IDDM20
Synonyms name lymphocyte adaptor protein
Locus 12q24, 12
Discovery year 2006-07-04
GenBank acession AF055581
Entrez gene record 10019
Pubmed identfication 10799879
RefSeq identity NM_005475
Classification Pleckstrin homology domain containing SH2 domain containing
Havana BLAST/BLAT OTTHUMG00000169550
Locus Specific Databases LRG_621

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