| Alternative name1 | Anti-GOAT ANTI HUMAN NCF1 |
| Alternative name2 | Caprine ANTI HUMAN NCF1 |
| Alternative name3 | Caprinae ANTI Homo sapiens NCF1 |
| Alternative name4 | NCF1 |
| Alternative name5 | N/A |
| Other names | (chronic granulomatous disease, 47 kDa autosomal chronic granulomatous disease protein, 47 kDa autosomal chronic granulomatous disease protein, 47 kDa neutrophil oxidase factor, 47 kDa neutrophil oxidase factor, NADPH oxidase organizer 2, NCF-1, NCF-47K, NCF-47K, Neutrophil NADPH oxidase factor 1, Neutrophil cytosol factor 1, Nox organizer 2, Nox-organizing protein 2, SH3 and PX domain-containing protein 1A, SH3 and PX domain-containing protein 1A, autosomal 1), neutrophil NADPH oxidase factor 1, neutrophil cytosol factor 1, neutrophil cytosolic factor 1, neutrophil cytosolic factor 1, nox organizer 2, nox-organizing protein 2, p47-phox, p47-phox, neutrophil cytosol factor 1 |
| Gene name | NCF1 |
| Gene name synonims | N/A |
| Other gene names | NCF-1, NCF1, NCF1A, NOXO2, NOXO2, SH3PXD1A, SH3PXD1A, p47phox, NCF1 |
| Category | Antibodies |
| Clonality | Polyclonal |
| Immunoglobulin isotype | Polyclonal IgG |
| Clone | Polyclonal antibody |
| Host organism | Goat |
| Species reactivity | Human |
| Specificity and cross-reactivity | Defects in NCF1 have been reported to be a cause of autosomal recessive chronic granulomatous disease, Expression of NCF1 is restricted to granulocytes, a 47kD cytosolic subunit of the multi-protein complex known as NADPH oxidase, monocytes and B lymphocytes, NCF1 This item recognises neutrophil cytosolic factor 1 (NCF1) |
| Purification method | N/A |
| Form/Appearance | Purified (Purified IgG - liquid) |
| Concentration | 5 mg/ml, IgG concentration 0 |
| Storage and shipping | Avoid repeated freezing and thawing as this may denature the antibody, Shelf Life: 18 months from date of dispatch, Should productone contain a precipitate we recommend microcentrifugation before use, Storage in frost-free freezers is not recommended, if preferred, or productone should be stored at -20 degrees Celsius, productone should be stored undiluted, Store at +Store productone at +4 degrees Celsius |
| Tested for: | Western Blot (WB) |
| Description | Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| Gene target | NCF1 |
| Short name | GOAT ANTI HUMAN NCF1 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | sapiens neutrophil cytosolic factor 1 (Antibody to), caprine antibody to H |
| Alternative technique | antibodies |
| Alternative to gene target | NCF1 and IDBG-21570 and ENSG00000158517 and 653361, NCF1 and IDBG-639883 and ENSBTAG00000003305 and 281345, Ncf1 and IDBG-202592 and ENSMUSG00000015950 and 17969, Plasma membranes, TAP-dependent and biological process this GO :0002679 and respiratory burst involved in defense response and biological process this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005791 and rough endoplasmic reticulum and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006612 and protein targeting to membrane and biological process this GO :0006691 and leukotriene metabolic process and biological process this GO :0006801 and superoxide metabolic process and biological process this GO :0006915 and apoptotic process and biological process this GO :0006954 and inflammatory response and biological process this GO :0006968 and cellular defense response and biological process this GO :0008283 and cell proliferation and biological process this GO :0009055 and electron carrier activity and molecular function this GO :0009617 and response to bacterium and biological process this GO :0016020 and membrane and cellular component this GO :0016175 and superoxide-generating NADPH oxidase activity and molecular function this GO :0017124 and SH3 domain binding and molecular function this GO :0019898 and extrinsic component of membrane and cellular component this GO :0030425 and dendrite and cellular component this GO :0032010 and pha this GO lysosome and cellular component this GO :0035091 and phosphatidylinositol binding and molecular function this GO :0042554 and superoxide anion generation and biological process this GO :0042590 and antigen processing and presentation of exogenous peptide antigen via MHC class I and biological process this GO :0042742 and defense response to bacterium and biological process this GO :0043020 and NADPH oxidase complex and cellular component this GO :0043025 and neuronal cell body and cellular component this GO :0043325 and phosphatidylinositol-3, phosphatidylinositol-3, this GO :0001878 and response to yeast and biological process this GO :0001909 and leukocyte mediated cytotoxicity and biological process this GO :0002474 and antigen processing and presentation of peptide antigen via MHC class I and biological process this GO :0002479 and antigen processing and presentation of exogenous peptide antigen via MHC class I, this GO :0005515: protein binding, this GO :0005515: protein binding and also this GO :0009055: electron carrier activity and also this GO :0016175: superoxide-generating NADPH oxidase activity and also this GO :0017124: SH3 domain binding and also this GO :0035091: phosphatidylinositol binding and also this GO :0043325: phosphatidylinositol-3, this GO :0009055: electron carrier activity, this GO :0016175: superoxide-generating NADPH oxidase activity, this GO :0017124: SH3 domain binding, this GO :0035091: phosphatidylinositol binding, this GO :0043325: phosphatidylinositol-3, 4-bisphosphate binding, 4-bisphosphate binding, 4-bisphosphate binding and molecular function this GO :0045087 and innate immune response and biological process this GO :0045730 and respiratory burst and biological process this GO :0045986 and negative regulation of smooth muscle contraction and biological process this GO :0050665 and hydrogen peroxide biosynthetic process and biological process this GO :0050830 and defense response to Gram-positive bacterium and biological process this GO :0050832 and defense response to fungus and biological process this GO :0051701 and interaction with host and biological process this GO :0055114 and oxidation-reduction process and biological process this GO :0070946 and neutrophil mediated killing of gram-positive bacterium and biological process this GO :0070947 and neutrophil mediated killing of fungus and biological process this GO :0090382 and pha this GO some maturation and biological process, neutrophil cytosolic factor 1 |
| Identity | 7660 |
| Gene | NCF1 |
| Long gene name | neutrophil cytosolic factor 1 |
| Synonyms gene name | autosomal 1) , chronic granulomatous disease, neutrophil cytosolic factor 1 (47kD |
| Synonyms | p47phox NOXO2 NCF1A SH3PXD1A |
| Synonyms name | NADPH oxidase organizer 2 chronic granulomatous disease, autosomal 1 |
| Locus | 7q11, 23 |
| Discovery year | 1989-05-25 |
| GenBank acession | M25665 |
| Entrez gene record | 653361 |
| RefSeq identity | NM_000265 |
| Havana BLAST/BLAT | OTTHUMG00000149965 |
| Locus Specific Databases | NCF1base: Mutation registry for autosomal recessive chronic granulomatous disease (CGD), deficiency of p47phox LRG_87 |
Technique
Supplier
Species
Label
Iso Type
Host
Tissue