| Alternative name1 | Anti-Goat Polyclonal to Human HER3 / ERBB3 |
| Alternative name2 | Caprine PAb to Human HER3 / ERBB3 |
| Alternative name3 | Caprinae Polyclonal to Homo sapiens HER3 / ERBB3 |
| Alternative name4 | HER3 / ERBB3 |
| Alternative name5 | C-erbB-3, C-erbB3, ERBB3, ERBB3, ErbB-3, ErbB3-S, HER3, Human HER3, LCCS2, MDA-BF-1, p180-ErbB3, p45-sErbB3, p85-sErbB3, Anti-HER3 / ERBB3 Antibody (C-Terminus) IHC-plus |
| Other names | Proto-oncogene-like protein c-ErbB-3, Receptor tyrosine-protein kinase erbB-3, Tyrosine kinase-type cell surface receptor HER3, erb-b2 receptor tyrosine kinase 3, human epidermal growth factor receptor 3, proto-oncogene-like protein c-ErbB-3, receptor tyrosine-protein kinase erbB-3, tyrosine kinase-type cell surface receptor HER3, v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3, receptor tyrosine-protein kinase erbB-3 isoform 1 |
| Gene name | HER3 |
| Gene name synonims | ERBB3 |
| Other gene names | ERBB3, ErbB-3, HER3, HER3, LCCS2, MDA-BF-1, c-erbB-3, c-erbB3, erbB3-S, p180-ErbB3, p45-sErbB3, p85-sErbB3, ERBB3 |
| Category | Antibodies |
| Clonality | Polyclonal |
| Immunoglobulin isotype | N/A |
| Clone | Polyclonal antibody |
| Host organism | Goat |
| Species reactivity | Bovine (at least 90% immunogen sequence identity), Gibbon, Hamster, Horse, Human, Monkey, Orangutan, Pig, Rat <, /b>, Bat, Mouse, Predicted Reactivity: <, b> |
| Specificity and cross-reactivity | This antibody is expected to recognise isoform 1 (NP_001973, 2) only, Human ERBB3 |
| Purification method | Immunoaffinity Purified |
| Form/Appearance | 0, 0, pH 7, 02% sodium azide, 3, 5% BSA, Tris-buffered saline |
| Concentration | 5 mg/ml |
| Storage and shipping | Minimize freezing and thawing, productone should be kept at -20 degrees Celsius, For optimal long term storage |
| Tested for: | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Description | Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties | Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24°, humans , ssp |
| Latin name | Capra aegagrus hircus |
| Group | Polyclonals and antibodies |
| About | The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera, immunohistochemistry on frozen slices or parrafin fixed tissues, Polyclonals can be used for Western blot |
| Gene target | HER3 / ERBB3 |
| Short name | Goat Polyclonal HER3 / ERBB3 Antibody |
| Technique | Pabs are a collection of immunoglobulin , Polyclonal antibodies , antibodies against human proteins, antibodies for, each identifying a different , goats, whereas , (pAbs) are mostly rabbit or goat , B cells, Polyclonal, antibodies , antigen, come from a single N cell lineage, epitope, molecules that react against a specific , monoclonal antibodies , that are secreted by different |
| Host | It are very good secondary antibodies that are affinity purified and have a good affinity themselves too, Often KLH is coupled to the antigen so anti KLH can be present in the vial, The goat polyclonal antibodies are directed against human genes or rabbit or mouse IgGs (H +L) chain primary antibodies and conjugated for detection, Goat |
| Species | Goats, Humans, Human |
| Alternative name | sapiens HER3 / v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) (Antibody to), caprine polyclonal to H |
| Alternative technique | polyclonals |
| Alternative to gene target | ERBB3 and IDBG-39824 and ENSG00000065361 and 2065, ERBB3 and IDBG-636302 and ENSBTAG00000010444 and 785655, Erbb3 and IDBG-197943 and ENSMUSG00000018166 and 13867, Extracellular, c-erbB-3 and c-erbB3 and ErbB-3 and erbB3-S and HER3 and LCCS2 and MDA-BF-1 and p180-ErbB3 and p45-sErbB3 and p85-sErbB3, this GO :0003197 and endocardial cushion development and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0004714 and transmembrane receptor protein tyrosine kinase activity and molecular function this GO :0004716 and receptor signaling protein tyrosine kinase activity and molecular function this GO :0004888 and transmembrane signaling receptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005615 and extracellular space and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0007162 and negative regulation of cell adhesion and biological process this GO :0007165 and signal transduction and biological process this GO :0007169 and transmembrane receptor protein tyrosine kinase signaling pathway and biological process this GO :0007173 and epidermal growth factor receptor signaling pathway and biological process this GO :0007422 and peripheral nervous system development and biological process this GO :0007507 and heart development and biological process this GO :0008543 and fibroblast growth factor receptor signaling pathway and biological process this GO :0009968 and negative regulation of signal transduction and biological process this GO :0014037 and Schwann cell differentiation and biological process this GO :0014065 and phosphatidylinositol 3-kinase signaling and biological process this GO :0014068 and positive regulation of phosphatidylinositol 3-kinase signaling and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016323 and basolateral plasma membrane and cellular component this GO :0016324 and apical plasma membrane and cellular component this GO :0016328 and lateral plasma membrane and cellular component this GO :0016772 and transferase activity, this GO :0004672: protein kinase activity, this GO :0004672: protein kinase activity and also this GO :0004713: protein tyrosine kinase activity and also this GO :0004714: transmembrane receptor protein tyrosine kinase activity and also this GO :0004716: receptor signaling protein tyrosine kinase activity and also this GO :0004888: transmembrane signaling receptor activity and also this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0016772: transferase activity, this GO :0004713: protein tyrosine kinase activity, this GO :0004714: transmembrane receptor protein tyrosine kinase activity, this GO :0004716: receptor signaling protein tyrosine kinase activity, this GO :0004888: transmembrane signaling receptor activity, this GO :0005515: protein binding, this GO :0005524: ATP binding, this GO :0016772: transferase activity, this GO :0019838: growth factor binding, this GO :0030296: protein tyrosine kinase activator activity, this GO :0042803: protein homodimerization activity, this GO :0046982: protein heterodimerization activity, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0019838: growth factor binding and also this GO :0030296: protein tyrosine kinase activator activity and also this GO :0042803: protein homodimerization activity and also this GO :0046982: protein heterodimerization activity, transferring phosphorus-containing groups and molecular function this GO :0018108 and peptidyl-tyrosine phosphorylation and biological process this GO :0019838 and growth factor binding and molecular function this GO :0021545 and cranial nerve development and biological process this GO :0030296 and protein tyrosine kinase activator activity and molecular function this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0042060 and wound healing and biological process this GO :0042127 and regulation of cell proliferation and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0043235 and receptor complex and cellular component this GO :0043524 and negative regulation of neuron apoptotic process and biological process this GO :0045087 and innate immune response and biological process this GO :0046982 and protein heterodimerization activity and molecular function this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0048015 and phosphatidylinositol-mediated signaling and biological process this GO :0051048 and negative regulation of secretion and biological process this GO :0051402 and neuron apoptotic process and biological process this GO :0061098 and positive regulation of protein tyrosine kinase activity and biological process this GO :0097192 and extrinsic apoptotic signaling pathway in absence of ligand and biological process, v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) |
| Identity | 3431 |
| Gene | ERBB3 |
| Long gene name | erb-b2 receptor tyrosine kinase 3 |
| Synonyms gene | LCCS2 |
| Synonyms gene name | lethal congenital contracture syndrome 2 v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3 |
| Synonyms | HER3 |
| Synonyms name | human epidermal growth factor receptor 3 |
| Locus | 12q13, 2 |
| Discovery year | 1990-07-15 |
| GenBank acession | M34309 |
| Entrez gene record | 2065 |
| RefSeq identity | NM_001982 |
| Classification | Erb-b2 receptor tyrosine kinases |
| Havana BLAST/BLAT | OTTHUMG00000170140 |
| Locus Specific Databases | LRG_996 |
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