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GPBAR1 Antibody

GPBAR1 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameGPBAR1 Primary Polyclonal Antibody
Also known asGPBAR1 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenGPCR TGR5/GPBAR1
SpecificityThis is a highly specific antibody against GPCR TGR5/GPBAR1
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Subcellular locationExtracellular
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GPBAR1
Gene ID number151306
Tested Applications FCM, IF(IHC-P), IHC-P, WB
Recommended dilutions FCM(1:20-100), IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivityHuman
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Bile acids activate mitogen-activated protein (MAP) kinase pathways, Bile acids also provoke TGR5 to suppress macrophage functions, TGR5 is sensitive to bile acids and responds through a significant mechanism that coordinates energy homeostasis, TGR5-controlled signaling pathways may be good candidates for drug targets to treat common metabolic diseases, and atherosclerosis, and cause rapid intracellular cAMP production, and leukocytes, but not in brain, colon (without mucosa), hyperlipidemia, kidney, liver, or lung, placenta, promote an increase of guanosine 5'-O-3-thio-triphosphate binding in membrane fractions, skeletal muscle, small intestine, specifically induce TGR5 internalization, spleen, such as obesity, thymus, type II diabetes, The G protein-coupled receptor TGR5 is a 330-amino acid protein that is almost universally expressed in human tissues including heart
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names BG37, G protein coupled bile acid receptor 1, G protein coupled bile acid receptor BG 37, G protein coupled bile acid receptor BG37, G-protein coupled bile acid receptor 1, G-protein coupled receptor GPCR19, GPBAR 1, GPBAR1, GPBAR_HUMAN, GPCR, GPCR 19, GPCR19, GPR 131, GPR131, M BAR, M-BAR, MGC40597, Membrane bile acid receptor, Membrane type receptor for bile acids, Membrane-type receptor for bile acids, TGR 5, TGR5, hBG 37, hBG37, hGPCR 19, hGPCR19, BG 37
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetGPBAR1
Short nameGPBAR1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameGPBAR1 (Antibody to)
Alternative techniqueantibodies
Identity 19680
Gene GPBAR1
Long gene name G protein-coupled bile acid receptor 1
Synonyms BG37 GPCR TGR5 M-BAR GPCR19 GPR131 MGC40597
Locus 2q35
Discovery year 2003-01-24
GenBank acession AB086170
Entrez gene record 151306
Pubmed identfication 12419312
RefSeq identity NM_001077191
Classification G protein-coupled bile acid receptor
Havana BLAST/BLAT OTTHUMG00000155203

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