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GPBAR1 Antibody, Cy7 Conjugated

GPBAR1 Antibody, Cy7 Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Cy7 Conjugated, GPBAR1 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationCy7
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenGPCR TGR5/GPBAR1
SpecificityThis is a highly specific antibody against GPCR TGR5/GPBAR1
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Subcellular locationExtracellular
SourceKLH conjugated synthetic peptide derived from human GPBAR1
Gene ID number151306
Tested applications IF(IHC-P), FCM
Recommended dilutions IF(IHC-P)(1:50-200), FCM(1:20-100)
CrossreactivityHuman
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Bile acids activate mitogen-activated protein (MAP) kinase pathways, Bile acids also provoke TGR5 to suppress macrophage functions, TGR5 is sensitive to bile acids and responds through a significant mechanism that coordinates energy homeostasis, TGR5-controlled signaling pathways may be good candidates for drug targets to treat common metabolic diseases, and atherosclerosis, and cause rapid intracellular cAMP production, and leukocytes, but not in brain, colon (without mucosa), hyperlipidemia, kidney, liver, or lung, placenta, promote an increase of guanosine 5'-O-3-thio-triphosphate binding in membrane fractions, skeletal muscle, small intestine, specifically induce TGR5 internalization, spleen, such as obesity, thymus, type II diabetes, The G protein-coupled receptor TGR5 is a 330-amino acid protein that is almost universally expressed in human tissues including heart
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission743nm/767nm
Synonyms BG37 GPCR TGR5 M-BAR GPCR19 GPR131 MGC40597
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
ConjugatedThese antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths
Gene targetGPBAR1 Conjugated
Short name Conjugated, GPBAR1 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy7
Alternative name cyanine 7 coupled, GPBAR1 (Antibody to)
Alternative techniqueantibodies
Identity 19680
Gene GPBAR1
Long gene name G protein-coupled bile acid receptor 1
Locus 2q35
Discovery year 2003-01-24
GenBank acession AB086170
Entrez gene record 151306
Pubmed identfication 12419312
RefSeq identity NM_001077191
Classification G protein-coupled bile acid receptor
Havana BLAST/BLAT OTTHUMG00000155203

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