Name : GPC3 scFv-CD28-CD3ζ
Supplier : 101BIOSYSTEM
Price :1468
SKU : GEN9885362755
Keep at | shipping: dry ice keep at: Liquid Nitrogen |
Expiry date | 12 m |
Use | For flow cytometry for killing cancer cells with CAR-T cells derived from chimeric Antigen Receptor T cells |
Gene target | GPC3 scFv-CD28-CD3&zeta |
Short name | GPC3 scFv-CD28-CD3&zeta |
Alternative name | glypican 3 scFv-CD28 molecule-CD3&zeta |
Alternative to gene target | CD28 and IDBG-643371 and ENSBTAG00000007445 and 281050, CD28 and IDBG-79183 and ENSG00000178562 and 940, Cd28 and IDBG-159608 and ENSMUSG00000026012 and 12487, Cell surfaces, DGSX and GTR2-2 and MXR7 and OCI-5 and SDYS and SGB and SGBS and SGBS1, Extracellular, GPC3 and IDBG-630953 and ENSBTAG00000020406 and 615239, GPC3 and IDBG-86754 and ENSG00000147257 and 2719, Gpc3 and IDBG-145213 and ENSMUSG00000055653 and 14734, Tp44, glypican 3, identical protein binding, peptidyl-dipeptidase inhibitor activity, planar cell polarity pathway and biological process, this GO :0001523 and retinoid metabolic process and biological process this GO :0001658 and branching involved in ureteric bud morphogenesis and biological process this GO :0001822 and kidney development and biological process this GO :0005515 and protein binding and molecular function this GO :0005578 and proteinaceous extracellular matrix and cellular component this GO :0005615 and extracellular space and cellular component this GO :0005764 and lysosome and cellular component this GO :0005796 and this GO lgi lumen and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0005975 and carbohydrate metabolic process and biological process this GO :0006024 and glycosaminoglycan biosynthetic process and biological process this GO :0006027 and glycosaminoglycan catabolic process and biological process this GO :0007603 and phototransduction, this GO :0001772 and immunological synapse and cellular component this GO :0002020 and protease binding and molecular function this GO :0002863 and positive regulation of inflammatory response to antigenic stimulus and biological process this GO :0005070 and SH3/SH2 adaptor activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0006959 and humoral immune response and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007173 and epidermal growth factor receptor signaling pathway and biological process this GO :0008543 and fibroblast growth factor receptor signaling pathway and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0009967 and positive regulation of signal transduction and biological process this GO :0015026 and coreceptor activity and molecular function this GO :0016032 and viral process and biological process this GO :0031295 and T cell costimulation and biological process this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0042089 and cytokine biosynthetic process and biological process this GO :0042102 and positive regulation of T cell proliferation and biological process this GO :0042802 and identical protein binding and molecular function this GO :0045060 and negative thymic T cell selection and biological process this GO :0045066 and regulatory T cell differentiation and biological process this GO :0045070 and positive regulation of viral genome replication and biological process this GO :0045086 and positive regulation of interleukin-2 biosynthetic process and biological process this GO :0045087 and innate immune response and biological process this GO :0045727 and positive regulation of translation and biological process this GO :0045840 and positive regulation of mitosis and biological process this GO :0045944 and positive regulation of transcription from RNA polymerase II promoter and biological process this GO :0046641 and positive regulation of alpha-beta T cell proliferation and biological process this GO :0048011 and neurotrophin TRK receptor signaling pathway and biological process this GO :0048015 and phosphatidylinositol-mediated signaling and biological process this GO :0048304 and positive regulation of isotype switching to IgG isotypes and biological process this GO :0050690 and regulation of defense response to virus by virus and biological process this GO :0050852 and T cell receptor signaling pathway and biological process this GO :0097190 and apoptotic signaling pathway and biological process, this GO :0002020: protease binding, this GO :0002020: protease binding and also this GO :0005070: SH3/SH2 adaptor activity and also this GO :0005515: protein binding and also this GO :0015026: coreceptor activity and also this GO :0042802: identical protein binding, this GO :0005070: SH3/SH2 adaptor activity, this GO :0005515: protein binding, this GO :0005515: protein binding, this GO :0005515: protein binding and also this GO :0043395: heparan sulfate proteoglycan binding and also this GO :0060422: peptidyl-dipeptidase inhibitor activity, this GO :0015026: coreceptor activity, this GO :0042802: identical protein binding, this GO :0043395: heparan sulfate proteoglycan binding, this GO :0060422: peptidyl-dipeptidase inhibitor activity, visible light and biological process this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0009653 and anatomical structure morphogenesis and biological process this GO :0009887 and organ morphogenesis and biological process this GO :0009948 and anterior/posterior axis specification and biological process this GO :0010171 and body morphogenesis and biological process this GO :0010466 and negative regulation of peptidase activity and biological process this GO :0016020 and membrane and cellular component this GO :0030203 and glycosaminoglycan metabolic process and biological process this GO :0030204 and chondroitin sulfate metabolic process and biological process this GO :0030282 and bone mineralization and biological process this GO :0030316 and osteoclast differentiation and biological process this GO :0030324 and lung development and biological process this GO :0030513 and positive regulation of BMP signaling pathway and biological process this GO :0035116 and embryonic hindlimb morphogenesis and biological process this GO :0040008 and regulation of growth and biological process this GO :0043202 and lysosomal lumen and cellular component this GO :0043395 and heparan sulfate proteoglycan binding and molecular function this GO :0044281 and small molecule metabolic process and biological process this GO :0045732 and positive regulation of protein catabolic process and biological process this GO :0045807 and positive regulation of endocytosis and biological process this GO :0045879 and negative regulation of smoothened signaling pathway and biological process this GO :0045880 and positive regulation of smoothened signaling pathway and biological process this GO :0045926 and negative regulation of growth and biological process this GO :0046326 and positive regulation of glucose import and biological process this GO :0046658 and anchored component of plasma membrane and cellular component this GO :0050680 and negative regulation of epithelial cell proliferation and biological process this GO :0060422 and peptidyl-dipeptidase inhibitor activity and molecular function this GO :0060976 and coronary vasculature development and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0072111 and cell proliferation involved in kidney development and biological process this GO :0072138 and mesenchymal cell proliferation involved in ureteric bud development and biological process this GO :0072180 and mesonephric duct morphogenesis and biological process this GO :0072203 and cell proliferation involved in metanephros development and biological process this GO :0090090 and negative regulation of canonical Wnt signaling pathway and biological process this GO :2000096 and positive regulation of Wnt receptor signaling pathway, CD28 molecule |
Identity | 4451 |
Gene | GPC3 |
Long gene name | glypican 3 |
Synonyms gene | SDYS |
Synonyms | OCI-5 SGBS SGBS1 SGB DGSX |
Synonyms name | glypican proteoglycan 3 |
Locus | Xq26, 2 |
Discovery year | 1996-08-08 |
GenBank acession | L47125 |
Entrez gene record | 2719 |
Pubmed identfication | 8589713 9787072 |
RefSeq identity | NM_004484 |
Classification | Glypicans |
Havana BLAST/BLAT | OTTHUMG00000022448 |
Locus Specific Databases | LRG_505 |