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GPCR G2A Antibody

GPCR G2A Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameGPCR G2A Primary Polyclonal Antibody
Also known asGPCR G2A PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenGPCR G2A
SpecificityThis is a highly specific antibody against GPCR G2A
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Subcellular locationExtracellular
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human G Protein Coupled Receptor G2A
Gene ID number29933
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivityHuman
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Ectopic expression of a G2A fusion protein in NIH/3T3 fibroblasts induces a cell cycle arrest that is consistent with a block at the G2/M transition (1, G2A is also able to attenuate the proliferative effects of Bcr-Abl, G2A is expressed throughout T cell maturation, G2A is predominantly expressed in hematopoietic tissues and in hematopoietic stem cells, The amino acid sequence of G2A contains a destruction box motif that is consistently observed in cyclins, a chimeric tyrosine kinase oncogene, and it is further increased in response to T-cell activation (3), and it is more highly detected in pro-B cells, suggesting that G2A possesses anti-oncogenic properties (5), where it is required for ubiquitination and proteolytic degradation (6), while lower expression is observed in immature B cells and pre-B cells (1, 2), 4), G2A (for G2 accumulation) is a seven transmembrane G protein-coupled receptor that is upregulated in response to DNA damage and stress (1)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names G Protein Coupled Receptor G2A, G2 accumulation protein, G2A, GP132_HUMAN, GPR132, Probable G-protein coupled receptor 132, G Protein Coupled Receptor G2A
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetGPCR G2A
Short nameGPCR G2A Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameGPCR G2A (Antibody to)
Alternative techniqueantibodies
Identity 24884
Gene OXER1
Long gene name oxoeicosanoid receptor 1
Synonyms GPCR TG1019 GPR170
Synonyms name 5-oxo-ETE acid G-protein-coupled receptor 1 OXE receptor
Locus 2p21
Discovery year 2004-04-02
GenBank acession AB083055
Entrez gene record 165140
Pubmed identfication 12065583 15001665
RefSeq identity NM_148962
Classification Leukotriene receptors
Havana BLAST/BLAT OTTHUMG00000128643

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