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GPCR G2A Antibody, Biotin Conjugated

GPCR G2A Antibody, Biotin Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name Biotin Conjugated, GPCR G2A Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenGPCR G2A
SpecificityThis is a highly specific antibody against GPCR G2A
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Subcellular locationExtracellular
SourceKLH conjugated synthetic peptide derived from human G Protein Coupled Receptor G2A
Gene ID number29933
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
CrossreactivityHuman
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Ectopic expression of a G2A fusion protein in NIH/3T3 fibroblasts induces a cell cycle arrest that is consistent with a block at the G2/M transition (1, G2A is also able to attenuate the proliferative effects of Bcr-Abl, G2A is expressed throughout T cell maturation, G2A is predominantly expressed in hematopoietic tissues and in hematopoietic stem cells, The amino acid sequence of G2A contains a destruction box motif that is consistently observed in cyclins, a chimeric tyrosine kinase oncogene, and it is further increased in response to T-cell activation (3), and it is more highly detected in pro-B cells, suggesting that G2A possesses anti-oncogenic properties (5), where it is required for ubiquitination and proteolytic degradation (6), while lower expression is observed in immature B cells and pre-B cells (1, 2), 4), G2A (for G2 accumulation) is a seven transmembrane G protein-coupled receptor that is upregulated in response to DNA damage and stress (1)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms GPCR TG1019 GPR170
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetGPCR G2A Conjugated
Short name Conjugated, GPCR G2A Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, GPCR G2A (Antibody to)
Alternative techniqueantibodies
Identity 24884
Gene OXER1
Long gene name oxoeicosanoid receptor 1
Synonyms name 5-oxo-ETE acid G-protein-coupled receptor 1 OXE receptor
Locus 2p21
Discovery year 2004-04-02
GenBank acession AB083055
Entrez gene record 165140
Pubmed identfication 12065583 15001665
RefSeq identity NM_148962
Classification Leukotriene receptors
Havana BLAST/BLAT OTTHUMG00000128643

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