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GPCR G2A Antibody, FITC Conjugated

GPCR G2A Antibody, FITC Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name FITC Conjugated, GPCR G2A Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenGPCR G2A
SpecificityThis is a highly specific antibody against GPCR G2A
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Subcellular locationExtracellular
SourceKLH conjugated synthetic peptide derived from human G Protein Coupled Receptor G2A
Gene ID number29933
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
CrossreactivityHuman
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Ectopic expression of a G2A fusion protein in NIH/3T3 fibroblasts induces a cell cycle arrest that is consistent with a block at the G2/M transition (1, G2A is also able to attenuate the proliferative effects of Bcr-Abl, G2A is expressed throughout T cell maturation, G2A is predominantly expressed in hematopoietic tissues and in hematopoietic stem cells, The amino acid sequence of G2A contains a destruction box motif that is consistently observed in cyclins, a chimeric tyrosine kinase oncogene, and it is further increased in response to T-cell activation (3), and it is more highly detected in pro-B cells, suggesting that G2A possesses anti-oncogenic properties (5), where it is required for ubiquitination and proteolytic degradation (6), while lower expression is observed in immature B cells and pre-B cells (1, 2), 4), G2A (for G2 accumulation) is a seven transmembrane G protein-coupled receptor that is upregulated in response to DNA damage and stress (1)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms GPCR TG1019 GPR170
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetGPCR G2A Conjugated
Short name FITC Conjugated, GPCR G2A Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, GPCR G2A (Antibody to)
Alternative techniqueantibodies
Identity 24884
Gene OXER1
Long gene name oxoeicosanoid receptor 1
Synonyms name 5-oxo-ETE acid G-protein-coupled receptor 1 OXE receptor
Locus 2p21
Discovery year 2004-04-02
GenBank acession AB083055
Entrez gene record 165140
Pubmed identfication 12065583 15001665
RefSeq identity NM_148962
Classification Leukotriene receptors
Havana BLAST/BLAT OTTHUMG00000128643

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