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GPNMB Antibody

GPNMB Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameGPNMB Primary Polyclonal Antibody
Also known asGPNMB PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenGPNMB
SpecificityThis is a highly specific antibody against GPNMB
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range85-135/572
Subcellular locationExtracellular
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human GPNMB
Gene ID number10457
Swiss ProtQ14956
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen GPNMB may be involved in growth delay and reduction of metastatic potential, GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines, Two transcript variants encoding different isoforms have been found for this gene, [provided by RefSeq], a melanocyte-specific protein, The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names GPNMB, HGFIN, Transmembrane glycoprotein HGFIN, Transmembrane glycoprotein NMB, UNQ1725/PRO9925, NMB
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetGPNMB
Short nameGPNMB Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameglycoprotein (transmembrane) nmb (Antibody to)
Alternative techniqueantibodies
Alternative to gene target BT, GPNMB and IDBG-9627 and ENSG00000136235 and 10457, Gpnmb and IDBG-146080 and ENSMUSG00000029816 and 93695, HGFIN and NMB, Plasma membranes, heparin binding, this GO :0001649 and osteoblast differentiation and biological process this GO :0005178 and integrin binding and molecular function this GO :0005887 and integral component of plasma membrane and cellular component this GO :0007155 and cell adhesion and biological process this GO :0008201 and heparin binding and molecular function this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0016021 and integral component of membrane and cellular component this GO :0016023 and cytoplasmic membrane-bounded vesicle and cellular component this GO :0030282 and bone mineralization and biological process this GO :0042470 and melanosome and cellular component, this GO :0005178: integrin binding, this GO :0005178: integrin binding and also this GO :0008201: heparin binding, this GO :0008201: heparin binding, 99652 and IDBG-630320 and ENSBTAG00000000604 and 509600, glycoprotein (transmembrane) nmb
Identity 4462
Gene GPNMB
Long gene name glycoprotein nmb
Synonyms gene name glycoprotein (transmembrane) nmb
Synonyms NMB HGFIN
Synonyms name transmembrane glycoprotein glycoprotein NMB glycoprotein nmb-like protein osteoactivin hematopoietic growth factor inducible neurokinin-1 glycoprotein nonmetastatic melanoma protein B
Locus 7p15, 3
Discovery year 1999-10-26
GenBank acession X76534
Entrez gene record 10457
Pubmed identfication 7814155
RefSeq identity NM_001005340
Havana BLAST/BLAT OTTHUMG00000022811

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